Balaji, Seshadri, DiLorenzo, Michael P., Fish, Frank A., Etheridge, Susan P., Aziz, Peter F., Russell, Mark W., Tisma, Svjetlana, Pflaumer, Andreas ORCID: 0000-0002-3830-3643, Sreeram, Narayanswami, Kubus, Peter, Law, Ian H., Kantoch, Michal J., Kertesz, Naomi J., Strieper, Margaret, Erickson, Christopher C., Moore, Jeremy P., Nakano, Stephanie J., Singh, Harinder R., Chang, Philip, Cohen, Mitchell, Fournier, Anne, Ilina, Maria V., Smith, Richard T., Zimmerman, Frank, Horndasch, Michaela, Li, Walter, Batra, Anjan, Liberman, Leonardo, Hamilton, Robert, Janson, Christopher M., Sanatani, Shubhayan ORCID: 0000-0001-9296-7400, Zeltser, Ilana, McDaniel, George, Blaufox, Andrew D., Garnreiter, Jason M., Katcoff, Hannah and Shah, Maully (2019). Impact of Obesity on Left Ventricular Thickness in Children with Hypertrophic Cardiomyopathy. Pediatr. Cardiol., 40 (6). S. 1253 - 1258. NEW YORK: SPRINGER. ISSN 1432-1971

Full text not available from this repository.

Abstract

Obesity is associated with additional left ventricular hypertrophy (LVH) in adults with hypertrophic cardiomyopathy (HCM). It is not known whether obesity can lead to further LVH in children with HCM. Echocardiographic LV dimensions were determined in 504 children with HCM. Measurements of interventricular septal thickness (IVST) and posterior wall thickness (PWT), and patients' weight and height were recorded. Obesity was defined as a body mass index (BMI) >= 99th percentile for age and sex. IVST data was available for 498 and PWT data for 484 patients. Patient age ranged from 2 to 20 years (mean +/- SD, 12.5 +/- 3.9) and 340 (68%) were males. Overall, patient BMI ranged from 7 to 50 (22.7 +/- 6.1). Obesity (BMI 18-50, mean 29.1) was present in 140 children aged 2-19.6 (11.3 +/- 4.1). The overall mean IVST was 20.5 +/- 9.6 mm and the overall mean PWT was 11.0 +/- 8.4 mm. The mean IVST in the obese patients was 21.6 +/- 10.0 mm and mean PWT was 13.3 +/- 14.7 mm. The mean IVST in the non-obese patients was 20.1 +/- 9.5 mm and mean PWT was 10.4 +/- 4.3 mm. Obesity was not significantly associated with IVST (p = 0.12), but was associated with increased PWT (0.0011). Obesity is associated with increased PWT but not IVST in children with HCM. Whether obesity and its impact on LVH influences clinical outcomes in children with HCM needs to be studied.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Balaji, SeshadriUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
DiLorenzo, Michael P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fish, Frank A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Etheridge, Susan P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aziz, Peter F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Russell, Mark W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tisma, SvjetlanaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pflaumer, AndreasUNSPECIFIEDorcid.org/0000-0002-3830-3643UNSPECIFIED
Sreeram, NarayanswamiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kubus, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Law, Ian H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kantoch, Michal J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kertesz, Naomi J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Strieper, MargaretUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Erickson, Christopher C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moore, Jeremy P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nakano, Stephanie J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Singh, Harinder R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chang, PhilipUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cohen, MitchellUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fournier, AnneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ilina, Maria V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Smith, Richard T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zimmerman, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horndasch, MichaelaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Li, WalterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Batra, AnjanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liberman, LeonardoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hamilton, RobertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Janson, Christopher M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sanatani, ShubhayanUNSPECIFIEDorcid.org/0000-0001-9296-7400UNSPECIFIED
Zeltser, IlanaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McDaniel, GeorgeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Blaufox, Andrew D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Garnreiter, Jason M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Katcoff, HannahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shah, MaullyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-145653
DOI: 10.1007/s00246-019-02145-9
Journal or Publication Title: Pediatr. Cardiol.
Volume: 40
Number: 6
Page Range: S. 1253 - 1258
Date: 2019
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1432-1971
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ASSOCIATION; MASS; GEOMETRYMultiple languages
Cardiac & Cardiovascular Systems; PediatricsMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14565

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item