Augustin, Max, Horn, Carola, Koch, Julian, de Silva, Ute Sandaradura, Platten, Martin, Nierhoff, Dirk, Suarez, Isabelle, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Rybniker, Jan and Lehmann, Clara (2019). Short Communication: Tracking Tregs: Translocation of CD49b/LAG-3(+) Type 1 T Regulatory Cells to the Gut-Associated Lymphoid Tissue of HIV+ Patients. Aids Res. Hum. Retrovir., 35 (3). S. 247 - 251. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1931-8405

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Abstract

The gastrointestinal mucosa [gut-associated lymphoid tissue (GALT)] represents the largest site of chronic immune activation and HIV replication. Important cellular agents in the immunopathogenesis of an HIV infection are, in particular, CD49b/LAG-3(+) type 1 T regulatory cells (Tr1), which secrete large amounts of IL-10 (interleukin-10), and plasmacytoid dendritic cells, the main producers of IFN-alpha (interferon-alpha). However, the distribution of CD49b/LAG-3(+) Tr1 cells along the GALT is unknown.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Augustin, MaxUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horn, CarolaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Koch, JulianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
de Silva, Ute SandaraduraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Platten, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nierhoff, DirkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Suarez, IsabelleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chon, Seung-HunUNSPECIFIEDorcid.org/0000-0002-8923-6428UNSPECIFIED
Rybniker, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lehmann, ClaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-154763
DOI: 10.1089/aid.2018.0052
Journal or Publication Title: Aids Res. Hum. Retrovir.
Volume: 35
Number: 3
Page Range: S. 247 - 251
Date: 2019
Publisher: MARY ANN LIEBERT, INC
Place of Publication: NEW ROCHELLE
ISSN: 1931-8405
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
INCREASED FREQUENCY; ACTIVATION; INFECTIONMultiple languages
Immunology; Infectious Diseases; VirologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/15476

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