Wahba, Roger, Suwelack, Barbara, Arns, Wolfgang, Cakiroglu, Figen, Eisenberger, Ute, Feldkamp, Thorsten, Hansen, Anita, Ivens, Kathrin, Klein, Thomas, Kribben, Andreas, Kurschat, Christine, Lange, Ulrich, Muehlfeld, Anja, Nitschke, Martin, Reuter, Stefan, Schulte, Kevin, Viebahn, Richard ORCID: 0000-0002-2051-0898, Woitas, Rainer, Hellmich, Martin and Stippel, Dirk L. (2017). Rescue allocation and recipient oriented extended allocation in kidney transplantation-influence of the EUROTRANSPLANT allocation system on recipient selection and graft survival for initially nonaccepted organs. Transpl. Int., 30 (12). S. 1226 - 1234. HOBOKEN: WILEY. ISSN 1432-2277

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Abstract

Nonaccepted kidneys grafts enter the rescue allocation (RA) process to avoid discards. In December 2013, recipient oriented extended allocation (REAL) was introduced to improve transparency. The aim of this study was to evaluate the influence of REAL on recipients selection and graft function compared to the formerly existing RA as well as to identify factors that influence graft outcome. Therefore, a multicenter study of 10 transplant centers in the same region in Germany was performed. All transplantations after RA or REAL from December 1, 2012, until December 31, 2014, with a follow-up time until December 31, 2015 were analyzed. 113 of 941 kidney transplantations were performed after RA or REAL (12%). With REAL, the number of refusals before transplantation had increased (12 +/- 7.1 vs. 8.6 +/- 8.6, P = 0.036), and cold ischemia time has decreased (13.6 +/- 3.6 vs. 17.2 +/- 4.8 h, P = 0.019). Recipients after REAL needed significantly more allocation points compared to RA to receive a kidney. One-year graft survival was comparable. If kidneys from the same donor were transplanted to two recipients at one center, the greater the difference in recipient age, the greater the difference in serum creatinine after 12 months (-0.019 mg/dl per year, P = 0.011) was, that is older recipients showed lower creatinine. REAL influences selection of the recipients compared to the former RA era for successful organ receipt. Graft function is comparable and seems to be influenced by recipient age.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wahba, RogerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Suwelack, BarbaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arns, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cakiroglu, FigenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eisenberger, UteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Feldkamp, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hansen, AnitaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ivens, KathrinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Klein, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kribben, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kurschat, ChristineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lange, UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Muehlfeld, AnjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nitschke, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reuter, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schulte, KevinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Viebahn, RichardUNSPECIFIEDorcid.org/0000-0002-2051-0898UNSPECIFIED
Woitas, RainerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hellmich, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stippel, Dirk L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-209928
DOI: 10.1111/tri.12993
Journal or Publication Title: Transpl. Int.
Volume: 30
Number: 12
Page Range: S. 1226 - 1234
Date: 2017
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1432-2277
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
OUTCOMES; DONOR; RISKMultiple languages
Surgery; TransplantationMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/20992

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