Universität zu Köln

Celik, Eren, Semrau, Robert, Baues, Christian, Trommer-Nestler, Maike, Baus, Wolfgang and Marnitz, Simone (2017). Robot-assisted Extracranial Stereotactic Radiotherapy of Adrenal Metastases in Oligometastatic Non-small Cell Lung Cancer. Anticancer Res., 37 (9). S. 5285 - 5292. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7530

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Abstract

Aim: The aim of this study was to evaluate the efficacy and toxicity of stereotactic body radiation therapy (SBRT) in the treatment of patients with adrenal metastases in oligometastatic non-small-cell lung cancer (NSCLC). Patients and Methods: Between November 2012 and May 2015, fifteen patients with oligometastatic non-small cell lung cancer and adrenal metastases were treated with the Cyberknife (R) system. The primary endpoint was local control. Results: The 1-year and 2-year local control rates were 60% and 46.6%, respectively. The differences in local control for patients with metachronous and synchronous metastases reached statistical significance (p= 0.00028). Two-year overall survival of 91.2% for patients with metachronous metastases was also more favourable compared to patients with synchronous adrenal metastases with 42.8%. Conclusion: Extracranial stereotactic radiotherapy with the Cyberknife (R) is a safe and non-invasive technique that extends the therapeutic spectrum in the treatment of patients with adrenal metastases in oligometastatic NSCLC.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Celik, Eren UNSPECIFIED UNSPECIFIED UNSPECIFIED Semrau, Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED Baues, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Trommer-Nestler, Maike UNSPECIFIED UNSPECIFIED UNSPECIFIED Baus, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED Marnitz, Simone UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-218380
DOI:	10.21873/anticanres.11954
Journal or Publication Title:	Anticancer Res.
Volume:	37
Number:	9
Page Range:	S. 5285 - 5292
Date:	2017
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7530
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BODY RADIATION-THERAPY; GLAND METASTASES; CARCINOMA; OUTCOMES; TUMORS; GUIDELINE; TRIAL; SBRT Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21838