Wiebe, Jens, Franke, Jennifer, Lubos, Edith, Boekstegers, Peter, Schillinger, Wolfgang, Ouarrak, Taoufik, May, Andreas E., Eggebrecht, Holger, Kuck, Karl-Heinz, Baldus, Stephan, Senges, Jochen and Sievert, Horst (2014). Percutaneous Mitral Valve Repair With the MitraClip System According to the Predicted Risk by the Logistic EuroSCORE: Preliminary Results From the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. Catheter. Cardiovasc. Interv., 84 (4). S. 591 - 599. HOBOKEN: WILEY. ISSN 1522-726X

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Abstract

Objective: To evaluate in-hospital and short-term outcomes of percutaneous mitral valve repair according to patients' logistic EuroSCORE (logEuroSCORE) in a multicenter registry Background: The logEuroSCORE is an established tool to predict the risk of mortality during cardiac surgery. In high-risk patients percutaneous mitral valve repair with the MitraClip system represents a less-invasive alternative Methods: Data from 1002 patients, who underwent percutaneous mitral valve repair with the MitraClip system, were analyzed in the German Transcatheter Mitral Valve Interventions (TRAMI) Registry. A logEuroSCORE (mortality risk in %) >= 20 was considered high risk Results: Of all patients, 557 (55.6%) had a logEuroSCORE >= 20. Implantation of the MitraClip was successful in 95.5 % (942/986) patients. Moderate residual mitral valve regurgitation was more often detected in patients with a logEuroSCORE >= 20 (23.8% vs. 17.1%, respectively, P < 0.05). In patients with a logEuroSCORE >= 20 the procedural complication rate was 8.9% (vs. 6.4, n.s.) and the in-hospital MACCE rate 4.9% (vs. 1.4% P < 0.01). The in-hospital mortality rate in patients with a logEuroSCORE >= 20 and logEuroSCORE < 20 was 4.3 and 1.1%, respectively (P <= 0.01) Conclusion: Percutaneous mitral valve repair with the MitraClip system is feasible in patients with a logEuroSCORE >= 20 with similar procedural results compared to patients with lower predicted risk. Although mortality was four times higher than in patients with logEuroSCORE < 20, mortality in high risk patients was lower than predicted. In those with a logEuroSCORE >= 20, moderate residual mitral valve regurgitation was more frequent. (C) 2014 Wiley Periodicals, Inc.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wiebe, JensUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Franke, JenniferUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lubos, EdithUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boekstegers, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schillinger, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ouarrak, TaoufikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
May, Andreas E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eggebrecht, HolgerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuck, Karl-HeinzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baldus, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Senges, JochenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sievert, HorstUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-427864
DOI: 10.1002/ccd.25493
Journal or Publication Title: Catheter. Cardiovasc. Interv.
Volume: 84
Number: 4
Page Range: S. 591 - 599
Date: 2014
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1522-726X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
LEARNING-CURVE; REGURGITATION; OUTCOMES; SURGERY; REPLACEMENT; THERAPY; LESSONS; SOCIETYMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/42786

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