Universität zu Köln

Eich, Marie-Lisa, Menter, Thomas, Mokwa, Nils Fabian, Gruettner, Berthold and Mueller, Annette M. (2022). Intrauterine fetal demise in extensive SARS-CoV-2-associated placental maternal vascular malperfusion in the setting of SARS-CoV-2 placentitis (severe acute respiratory syndrome coronavirus 2). Pathologe, 43 (2). S. 135 - 140. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1963

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Abstract

We report a case of a placenta with extensive maternal vascular malperfusion and chronic histiocytic intervillositis corresponding to SARS-CoV-2 placentitis in the context of fetal demise at 31 weeks of gestation. Placental swamp and PCR of the placental parenchyma, umbilical cord and amnion-chorion membrane showed SARS-CoV-2- and B-betacoronavirus-specific RNA. Maternal vascular malperfusion has been described in cases of SARS-CoV-2 infection; however, the manifested severity of this case in the setting of a severe SARS-CoV-2 placentitis is rare. It emphasizes the need of a maternal prophylactic anticoagulation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Eich, Marie-Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Menter, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Mokwa, Nils Fabian UNSPECIFIED UNSPECIFIED UNSPECIFIED Gruettner, Berthold UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, Annette M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-575289
DOI:	10.1007/s00292-021-01035-3
Journal or Publication Title:	Pathologe
Volume:	43
Number:	2
Page Range:	S. 135 - 140
Date:	2022
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-1963
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language COVID-19 Multiple languages Pathology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57528