Barragan, Eduardo, Breuer, Dieter and Doepfner, Manfred (2017). Efficacy and Safety of Omega-3/6 Fatty Acids, Methylphenidate, and a Combined Treatment in Children With ADHD. J. Atten. Disord., 21 (5). S. 433 - 442. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1557-1246
Full text not available from this repository.Abstract
Objective: To compare efficacy of Omega-3/6 fatty acids (Equazen eye q (TM)) with methylphenidate (MPH) and combined MPH + Omega-3/6 in children with ADHD. Method: Participants (N = 90) were randomized to Omega-3/6, long-acting MPH, or combination for 12 months. ADHD symptoms were assessed using the ADHD Rating Scale and Clinical Global Impressions-Severity (CGI-S) scale. Results: ADHD symptoms decreased in all treatment arms. Although significant differences favoring Omega + MPH over Omega-3/6 alone were found for ADHD Total and Hyperactivity-Impulsivity subscales, results on the Inattention subscale were similar. CGI-S scores decreased slowly and consistently with Omega-3/6, compared with a rapid decrease and subsequent slight increase in the MPH-containing arms. Adverse events were numerically less frequent with Omega-3/6 or MPH + Omega-3/6 than MPH alone. Conclusion: The tested combination of Omega-3/6 fatty acids had similar effects to MPH, whereas the MPH + Omega combination appeared to have some tolerability benefits over MPH.
Item Type: | Journal Article | ||||||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-232988 | ||||||||||||||||
DOI: | 10.1177/1087054713518239 | ||||||||||||||||
Journal or Publication Title: | J. Atten. Disord. | ||||||||||||||||
Volume: | 21 | ||||||||||||||||
Number: | 5 | ||||||||||||||||
Page Range: | S. 433 - 442 | ||||||||||||||||
Date: | 2017 | ||||||||||||||||
Publisher: | SAGE PUBLICATIONS INC | ||||||||||||||||
Place of Publication: | THOUSAND OAKS | ||||||||||||||||
ISSN: | 1557-1246 | ||||||||||||||||
Language: | English | ||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||
Subjects: | no entry | ||||||||||||||||
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Refereed: | Yes | ||||||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/23298 |
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