Universität zu Köln

Grajewski, R. S., Boelke, A. C., Adler, W., Meyer, S., Caramoy, A., Kirchhof, B., Cursiefen, C. and Heindl, L. M. (2016). Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis. Eye, 30 (11). S. 1415 - 1424. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5454

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Abstract

Purpose To analyze the macular structure in a large series of consecutive patients with different types of uveitis using spectral-domain optical coherence tomography (SD-OCT). Patients and methods Five hundred eyes of 500 consecutive patients with anterior, intermediate, posterior, and panuveitis underwent standardized macular examination using SD-OCT. Central retinal thickness (CRT), macular volume (MV), and presence of cystoid macular edema (CME), diffuse macular edema (DME), serous retinal detachment (SRD), epiretinal membrane with (ERM+) and without (ERM-) retinal surface wrinkling were determined. Results The anatomic location of inflammation affected significantly CRT and MV (P<0.001, respectively), with the highest values in intermediate and panuveitis. CME was seen in 25% of all uveitic eyes, DME in 11%, SRD in 8%, ERM+ in 18%, and ERM - in 13%. CME was most frequent in intermediate (40%) and panuveitis (36%); DME was most frequent in panuveitis (18%) and posterior uveitis (17%); SRD was most frequent in panuveitis (15%) and posterior uveitis (10%); ERM+ was most frequent in panuveitis (45%) and intermediate uveitis (30%); and ERM - was most frequent in intermediate (14%) and posterior uveitis (15%). Conclusion SD-OCT of the macula is recommended for all uveitis patients. CRT, MV, and the incidence of CME were highest in intermediate and panuveitis.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Grajewski, R. S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boelke, A. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Adler, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Meyer, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Caramoy, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kirchhof, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, L. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-257731
DOI:	10.1038/eye.2016.133
Journal or Publication Title:	Eye
Volume:	30
Number:	11
Page Range:	S. 1415 - 1424
Date:	2016
Publisher:	NATURE PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1476-5454
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EDEMA; DIAGNOSIS; RECOMMENDATIONS; RESOLUTION; CRITERIA Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/25773