Malter, Michael, Neuneier, Janina, Triller, Annika and Kallweit, Ulf . Narcolepsy in adults: Definition, etiology and treatment. Forschritte Neurol. Psychiatr.. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3522
Full text not available from this repository.Abstract
Zusammenfassung Narkolepsie ist eine Hypersomnolenz-Erkrankung, die mit einer Storung der Wach-Schlaf-Regulation einhergeht. Leitsymptome sind exzessive Tagesschlafrigkeit und Kataplexien. Zudem treten hypnagogene/hypnopompe Halluzinationen, Schlaflahmungen und gestorter Nachtschlaf auf. Es werden zwei Formen unterschieden. Bei der Narkolepsie Typ 1, fruher Narkolepsie mit Kataplexie, besteht eine Hypocretin-Defizienz. Die Ursache der Narkolepsie Typ 2, fruher Narkolepsie ohne Kataplexie, ist im Wesentlichen ungeklart. Zur Diagnosestellung ist ein multimodaler Ansatz notwendig. Die Latenz zwischen Erkrankungsbeginn und Diagnosestellung in Europa betragt im Mittel 14 Jahre. Es bestehen erhebliche Probleme in der Versorgung von Menschen mit Narkolepsie. Die in aller Regel lebenslange Behandlung der Narkolepsie umfasst sowohl nichtmedikamentose Strategien als auch die symptomatische medikamentose Behandlung. Abstract Narcolepsy is a hypersomnolence disorder of central origin that presents with a disturbance of the wake-sleep regulation. Lead symptoms consist of excessive daytime sleepiness and cataplexy. Nowadays, two types of narcolepsy are distinguished. Type 1 narcolepsy, formerly known as narcolepsy with cataplexy, is based on hypocretin deficiency. The cause of type 2 narcolepsy, formerly known as narcolepsy without cataplexy, remains mainly unknown. A multimodal approach is necessary for diagnosis. The mean latency between the onset of disease and diagnosis in Europe ranges 14 years. Narcolepsy has a major impact on workability and quality of life. The management of narcolepsy is usually life-long and includes non-pharmacological approaches and a symptomatic pharmacological treatment.
Item Type: | Journal Article | ||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-307759 | ||||||||||||||||||||
DOI: | 10.1055/a-1244-2612 | ||||||||||||||||||||
Journal or Publication Title: | Forschritte Neurol. Psychiatr. | ||||||||||||||||||||
Publisher: | GEORG THIEME VERLAG KG | ||||||||||||||||||||
Place of Publication: | STUTTGART | ||||||||||||||||||||
ISSN: | 1439-3522 | ||||||||||||||||||||
Language: | German | ||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/30775 |
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