Universität zu Köln

Journal Article

Brenke, Jara K., Salmina, Elena S., Ringelstetter, Larissa, Dornauer, Scarlett, Kuzikov, Maria, Rothenaigner, Ina, Schorpp, Kenji, Giehler, Fabian, Gopalakrishnan, Jay, Kieser, Arnd ORCID: 0000-0003-0783-1950, Gul, Sheraz, Tetko, Igor V. ORCID: 0000-0002-6855-0012 and Hadian, Kamyar ORCID: 0000-0001-8727-2575 (2016). Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase-Glutathione Interaction. J. Biomol. Screen, 21 (6). S. 596 - 608. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1552-454X

Carrera, Lilian A. Martinez, Gabriel, Elke, Donohoe, Colin D., Hoelker, Irmgard, Mariappan, Aruljothi, Storbeck, Markus, Uhlirova, Mirka ORCID: 0000-0002-5735-8287, Gopalakrishnan, Jay and Wirth, Brunhilde ORCID: 0000-0003-4051-5191 (2018). Novel insights into SMALED2: BICD2 mutations increase microtubule stability and cause defects in axonal and NMJ development. Hum. Mol. Genet., 27 (10). S. 1772 - 1785. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Farooq, Muhammad, Lindbaek, Louise, Krogh, Nicolai ORCID: 0000-0001-8870-7091, Doganli, Canan, Keller, Cecilie, Monnich, Maren, Goncalves, Andre Bras, Sakthivel, Srinivasan, Mang, Yuan, Fatima, Ambrin, Andersen, Vivi Sogaard, Hussain, Muhammad S., Eiberg, Hans, Hansen, Lars, Kjaer, Klaus Wilbrandt, Gopalakrishnan, Jay, Pedersen, Lotte Bang, Mollgard, Kjeld, Nielsen, Henrik, Baig, Shahid M., Tommerup, Niels, Christensen, Soren Tvorup and Larsen, Lars Allan (2020). RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis. Nat. Commun., 11 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723

Gabriel, Elke, Albanna, Walid, Pasquini, Giovanni ORCID: 0000-0002-5750-6307, Ramani, Anand, Josipovic, Natasa ORCID: 0000-0001-7683-0869, Mariappan, Aruljothi, Schinzel, Friedrich, Karch, Celeste M., Bao, Guobin, Gottardo, Marco, Suren, Ata Alp, Hescheler, Jurgen, Nagel-Wolfrum, Kerstin, Persico, Veronica, Rizzoli, Silvio O., Altmuller, Janine, Riparbelli, Maria Giovanna, Callaini, Giuliano, Goureau, Olivier, Papantonis, Argyris, Busskamp, Volker, Schneider, Toni and Gopalakrishnan, Jay (2021). Human brain organoids assemble functionally integrated bilateral optic vesicles. Cell Stem Cell, 28 (10). S. 1740 - 1767. CAMBRIDGE: CELL PRESS. ISSN 1875-9777

Gabriel, Elke and Gopalakrishnan, Jay (2017). Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders. J. Vis. Exp. (122). CAMBRIDGE: JOURNAL OF VISUALIZED EXPERIMENTS. ISSN 1940-087X

Gabriel, Elke, Ramani, Anand, Karow, Ulrike, Gottardo, Marco ORCID: 0000-0001-8649-7799, Natarajan, Karthick, Gooi, Li Ming, Goranci-Buzhala, Gladiola, Krut, Oleg, Peters, Franziska, Nikolic, Milos ORCID: 0000-0003-0029-7601, Kuivanen, Suvi, Korhonen, Essi ORCID: 0000-0003-4730-7715, Smura, Teemu ORCID: 0000-0002-9187-3151, Vapalahti, Olli ORCID: 0000-0003-2270-6824, Papantonis, Argyris ORCID: 0000-0001-7551-1073, Schmidt-Chanasit, Jonas, Riparbelli, Maria, Callaini, Giuliano ORCID: 0000-0003-2252-0309, Kroenke, Martin, Utermoehlen, Olaf and Gopalakrishnan, Jay (2017). Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. Cell Stem Cell, 20 (3). S. 397 - 412. CAMBRIDGE: CELL PRESS. ISSN 1875-9777

Gabriel, Elke, Wason, Arpit, Ramani, Anand, Gooi, Li Ming, Keller, Patrick, Pozniakovsky, Andrei, Poser, Ina, Noack, Florian, Telugu, Narasimha Swamy, Calegari, Federico, Saric, Tomo ORCID: 0000-0001-8344-1095, Hescheler, Juergen, Hyman, Anthony A., Gottardo, Marco ORCID: 0000-0001-8649-7799, Callaini, Giuliano ORCID: 0000-0003-2252-0309, Alkuraya, Fowzan Sami and Gopalakrishnan, Jay (2016). CPAP promotes timely cilium disassembly to maintain neural progenitor pool. Embo J., 35 (8). S. 803 - 820. HOBOKEN: WILEY-BLACKWELL. ISSN 1460-2075

Gooi, Li Ming and Gopalakrishnan, Jay (2016). Regulation of Stem Cells in Their Niche. Curr. Stem. Cell Rep., 2 (3). S. 282 - 290. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 2198-7866

Goranci-Buzhala, Gladiola, Gabriel, Elke, Mariappan, Aruljothi and Gopalakrishnan, Jay (2017). Losers of Primary Cilia Gain the Benefit of survival. Cancer Discov., 7 (12). S. 1374 - 1376. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290

Goranci-Buzhala, Gladiola, Mariappan, Aruljothi, Ricci-Vitiani, Lucia, Josipovic, Natasa ORCID: 0000-0001-7683-0869, Pacioni, Simone, Gottardo, Marco, Ptok, Johannes, Schaal, Heiner, Callaini, Giuliano, Rajalingam, Krishnaraj, Dynlacht, Brian, Hadian, Kamyar ORCID: 0000-0001-8727-2575, Papantonis, Argyris, Pallini, Roberto and Gopalakrishnan, Jay (2021). Cilium induction triggers differentiation of glioma stem cells. Cell Reports, 36 (10). CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Mariappan, Aruljothi, Soni, Komal, Schorpp, Kenji, Zhao, Fan, Minakar, Amin, Zheng, Xiangdong, Mandad, Sunit, Macheleidt, Iris, Ramani, Anand, Kubelka, Tomas ORCID: 0000-0003-1881-5171, Dawidowski, Maciej ORCID: 0000-0002-7262-5718, Golfmann, Kristina, Wason, Arpit, Yang, Chunhua, Simons, Judith, Schmalz, Hans-Guenther ORCID: 0000-0003-0489-1827, Hyman, Anthony A., Aneja, Ritu, Ullrich, Roland, Urlaub, Henning, Odenthal, Margarete, Buettner, Reinhardt, Li, Haitao ORCID: 0000-0001-6741-293X, Sattler, Michael ORCID: 0000-0002-1594-0527, Hadian, Kamyar and Gopalakrishnan, Jay (2019). Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells. Embo J., 38 (2). HOBOKEN: WILEY. ISSN 1460-2075

Ramani, Anand, Mariappan, Aruljothi, Gottardo, Marco, Mandad, Sunit, Urlaub, Henning, Avidor-Reiss, Tomer ORCID: 0000-0003-0918-526X, Riparbelli, Maria, Callaini, Giuliano, Debec, Alain, Feederle, Regina and Gopalakrishnan, Jay (2018). Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes. Cell Reports, 25 (13). S. 3618 - 3637. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Ramani, Anand, Mueller, Lisa, Ostermann, Philipp N., Gabriel, Elke, Abida-Islam, Pranty, Mueller-Schiffmann, Andreas, Mariappan, Aruljothi, Goureau, Olivier, Gruell, Henning, Walker, Andreas, Andree, Marcel, Hauka, Sandra, Houwaart, Torsten, Dilthey, Alexander, Wohlgemuth, Kai, Omran, Heymut, Klein, Florian, Wieczorek, Dagmar, Adams, Ortwin, Timm, Joerg, Korth, Carsten, Schaal, Heiner and Gopalakrishnan, Jay (2020). SARS-CoV-2 targets neurons of 3D human brain organoids. Embo J., 39 (20). HOBOKEN: WILEY. ISSN 1460-2075

Schorpp, Kenji, Rothenaigner, Ina, Salmina, Elena ORCID: 0000-0002-3526-4378, Reinshagen, Jeanette, Low, Terence, Brenke, Jara K., Gopalakrishnan, Jay, Tetko, Igor V. ORCID: 0000-0002-6855-0012, Gul, Sheraz and Hadian, Kamyar ORCID: 0000-0001-8727-2575 (2014). Identification of Small-Molecule Frequent Hitters from AlphaScreen High-Throughput Screens. J. Biomol. Screen, 19 (5). S. 715 - 727. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1552-454X

Stein, Andreas, Thomopoulou, Persefoni Hilken Nee, Frias, Corazon, Hopff, Sina M., Varela, Paloma ORCID: 0000-0001-5078-7102, Wilke, Nicola ORCID: 0000-0003-2832-7374, Mariappan, Arul, Neudoerfl, Jorg-Martin, Fedorov, Alexey Yu, Gopalakrishnan, Jay ORCID: 0000-0001-5907-3982, Gigant, Benoit ORCID: 0000-0002-5946-6759, Prokop, Aram and Schmalz, Hans-Gunther (2022). B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner. ACS Omega, 7 (3). S. 2591 - 2604. WASHINGTON: AMER CHEMICAL SOC. ISSN 2470-1343

Sudhakar, Digumarthi V. S., Phanindranath, Regur, Jaishankar, Shveta, Ramani, Anand, Kalamkar, Kaustubh P., Kumar, Umesh, Pawar, Asmita D., Dada, Rima, Singh, Rajender, Gupta, Nalini J., Deenadayal, Mamata, Tolani, Aarti Deenadayal, Sharma, Yogendra, Anand, Anuranjan, Gopalakrishnan, Jay ORCID: 0000-0001-5907-3982 and Thangaraj, Kumarasamy . Exome sequencing and functional analyses revealed CETN1 variants leads to impaired cell division and male fertility. Hum. Mol. Genet.. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Thomopoulou, Persefoni, Sachs, Julia, Teusch, Nicole ORCID: 0000-0002-9030-1493, Mariappan, Aruljothi, Gopalakrishnan, Jay and Schmalz, Hans-Guenther ORCID: 0000-0003-0489-1827 (2016). New Colchicine-Derived Triazoles and Their Influence on Cytotoxicity and Microtubule Morphology. ACS Med. Chem. Lett., 7 (2). S. 188 - 192. WASHINGTON: AMER CHEMICAL SOC. ISSN 1948-5875

Wike, Candice L., Graves, Hillary K., Wason, Arpit, Hawkins, Reva, Gopalakrishnan, Jay, Schumacher, Jill and Tyler, Jessica K. (2016). Excess free histone H3 localizes to centrosomes for proteasome-mediated degradation during mitosis in metazoans. Cell Cycle, 15 (16). S. 2216 - 2226. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1551-4005

Zheng, Xiangdong, Gooi, Li Ming, Wason, Arpit, Gabriel, Elke, Mehrjardi, Narges Zare, Yang, Qian, Zhang, Xingrun, Debec, Alain, Basiri, Marcus L., Avidor-Reiss, Tomer ORCID: 0000-0003-0918-526X, Pozniakovsky, Andrei, Poser, Ina, Saric, Tomo ORCID: 0000-0001-8344-1095, Hyman, Anthony A., Li, Haitao ORCID: 0000-0001-6741-293X and Gopalakrishnan, Jay (2014). Conserved TCP domain of Sas-4/CPAP is essential for pericentriolar material tethering during centrosome biogenesis. Proc. Natl. Acad. Sci. U. S. A., 111 (3). S. E354 - 10. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Zheng, Xiangdong, Ramani, Anand, Soni, Komal, Gottardo, Marco ORCID: 0000-0001-8649-7799, Zheng, Shuangping, Gooi, Li Ming, Li, Wenjing, Feng, Shan, Mariappan, Aruljothi, Wason, Arpit, Widlund, Per ORCID: 0000-0002-3645-0009, Pozniakovsky, Andrei, Poser, Ina, Deng, Haiteng ORCID: 0000-0001-9496-1280, Ou, Guangshuo, Riparbelli, Maria, Giuliano, Callaini, Hyman, Anthony A., Sattler, Michael ORCID: 0000-0002-1594-0527, Gopalakrishnan, Jay and Li, Haitao ORCID: 0000-0001-6741-293X (2016). Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length. Nat. Commun., 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723