Doepfner, Manfred, Dose, Christina, Breuer, Dieter, Heintz, Stefan, Schiffhauer, Stefanie and Banaschewski, Tobias . Efficacy of Omega-3/Omega-6 Fatty Acids in Preschool Children at Risk of ADHD: A Randomized Placebo-Controlled Trial. J. Atten. Disord.. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1557-1246

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Abstract

Objective: To evaluate the efficacy of an Omega-3/Omega-6 fatty acid supplement in preschool children at risk for ADHD. Method: Forty preschool children with elevated levels of ADHD symptoms were randomly assigned to either a verum or a placebo group. Children in the verum group received a 4-month treatment with Omega-3/Omega-6 fatty acids. Outcome measures comprised parent- and teacher-rated ADHD symptoms, which were the primary outcome variables, internalizing and externalizing problems, and intellectual abilities. Results: Intention-to-treat analyses of covariance, controlling for age and baseline data, revealed effects on parent- and teacher-rated ADHD symptoms (primary outcomes; parent ratings: F = 4.51, df = 1, p = .04, d = 0.63; teacher ratings: F = 4.67, df = 1, p = .04, d = 0.70), parent-rated internalizing symptoms (F = 8.47, df = 1, p < .01, d = 0.63), and parent- and teacher-rated externalizing symptoms (parent ratings: F = 4.58, df = 1, p = .04, d = 0.54; teacher ratings: F = 5.99, df = 1, p = .02, d = 0.79). Analyses involving only cases with available data yielded significant moderate effects on teacher-rated inattention symptoms (F = 4.60, df = 1, p = .04, d = 0.79) and parent-rated internalizing problems (F = 6.04, df = 1, p = .02, d = 0.57). Conclusion: The intention-to-treat analyses provide some evidence for positive effects of Omega-3/Omega-6 fatty acids. However, the results require replication in larger samples to allow for firm conclusions for practice.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Doepfner, ManfredUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dose, ChristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Breuer, DieterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heintz, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schiffhauer, StefanieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Banaschewski, TobiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-128286
DOI: 10.1177/1087054719883023
Journal or Publication Title: J. Atten. Disord.
Publisher: SAGE PUBLICATIONS INC
Place of Publication: THOUSAND OAKS
ISSN: 1557-1246
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT-HYPERACTIVITY DISORDER; BEHAVIOR PROBLEMS; SUPPLEMENTATION; METHYLPHENIDATE; IMMEDIATE; APPRAISAL; DIETARY; SAFETYMultiple languages
Psychology, Developmental; PsychiatryMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/12828

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