Goertz, Lukas, Hamisch, Christina, Pflaeging, Muriel, Kabbasch, Christoph ORCID: 0000-0003-3712-2258, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Timmer, Marco, Stravrinou, Pantelis, Goldbrunner, Roland, Brinker, Gerrit, Mpotsaris, Anastasios and Krischek, Boris (2019). Angiographic Characteristics of Lobulated Intracranial Aneurysms. World Neurosurg., 131. S. E353 - 9. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-8769

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Abstract

OBJECTIVE: Previous studies have indicated that lobulated aneurysms are more susceptible to rupture than are single-sac aneurysms. We aimed to determine the angiographic characteristics related to the lobulated shape of unruptured intracranial aneurysms (UIAs) and ruptured (RIAs) intracranial aneurysms. METHODS: This is a retrospective analysis of consecutive patients with UIAs (n = 143) and RIAs in = 190) who underwent digital subtraction angiography at our institution between 2010 and 2017. Patient and aneurysm characteristics were compared between lobulated and regular single-sac aneurysms. RESULTS: Patients with lobulated UIAs were significantly older than were patients with regular aneurysms (56.5 +/- 10.7 years vs. 49.3 +/- 13.0 years; P = 0.003). In the multivariate analysis, lobulated morphology was significantly related to bifurcation location (69.5% vs. 27.3%; odds ratio [OR], 3.0, 95% confidence interval [CI], 1.2-7.5; P = 0.019), aneurysm size (8.1 +/- 3.2 mm vs. 4.9 +/- 3.0 mm; OR, 5.4; 95% CI, 1.7-17.8; P = 0.005), and inflow angle (145 +/- 27 vs. 114 +/- 27 ; OR, 2.8; 95% CI, 1.1-7.2; P = 0.031). Bifurcation location (P = 0.031) and larger aneurysm size (P < 0.001) were confirmed as independent characteristics for lobulation in the RIA group. Compared with regular aneurysms, lobulated UIAs were more often allocated to treatment (86.6% vs. 60.3%; P < 0.001) and treated by microsurgical clipping (39.4% vs. 16.4%; P = 0.002). CONCLUSIONS: Bifurcation location, an increased aneurysm size, and a straighter aneurysm inflow angle are independently associated with lobulated aneurysms.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Goertz, LukasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hamisch, ChristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pflaeging, MurielUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabbasch, ChristophUNSPECIFIEDorcid.org/0000-0003-3712-2258UNSPECIFIED
Borggrefe, JanUNSPECIFIEDorcid.org/0000-0003-2908-7560UNSPECIFIED
Timmer, MarcoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stravrinou, PantelisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goldbrunner, RolandUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Brinker, GerritUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mpotsaris, AnastasiosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krischek, BorisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-129747
DOI: 10.1016/j.wneu.2019.07.163
Journal or Publication Title: World Neurosurg.
Volume: 131
Page Range: S. E353 - 9
Date: 2019
Publisher: ELSEVIER SCIENCE INC
Place of Publication: NEW YORK
ISSN: 1878-8769
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
UNRUPTURED CEREBRAL ANEURYSMS; RISK-FACTORS; PERIANEURYSMAL ENVIRONMENT; NATURAL-HISTORY; IRREGULAR SHAPE; PHASES SCORE; RUPTURE; GROWTH; BIFURCATION; PREDICTIONMultiple languages
Clinical Neurology; SurgeryMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/12974

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