Goertz, Lukas, Hamisch, Christina, Pflaeging, Muriel, Kabbasch, Christoph ORCID: 0000-0003-3712-2258, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Timmer, Marco, Stravrinou, Pantelis, Goldbrunner, Roland, Brinker, Gerrit, Mpotsaris, Anastasios and Krischek, Boris (2019). Angiographic Characteristics of Lobulated Intracranial Aneurysms. World Neurosurg., 131. S. E353 - 9. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1878-8769
Full text not available from this repository.Abstract
OBJECTIVE: Previous studies have indicated that lobulated aneurysms are more susceptible to rupture than are single-sac aneurysms. We aimed to determine the angiographic characteristics related to the lobulated shape of unruptured intracranial aneurysms (UIAs) and ruptured (RIAs) intracranial aneurysms. METHODS: This is a retrospective analysis of consecutive patients with UIAs (n = 143) and RIAs in = 190) who underwent digital subtraction angiography at our institution between 2010 and 2017. Patient and aneurysm characteristics were compared between lobulated and regular single-sac aneurysms. RESULTS: Patients with lobulated UIAs were significantly older than were patients with regular aneurysms (56.5 +/- 10.7 years vs. 49.3 +/- 13.0 years; P = 0.003). In the multivariate analysis, lobulated morphology was significantly related to bifurcation location (69.5% vs. 27.3%; odds ratio [OR], 3.0, 95% confidence interval [CI], 1.2-7.5; P = 0.019), aneurysm size (8.1 +/- 3.2 mm vs. 4.9 +/- 3.0 mm; OR, 5.4; 95% CI, 1.7-17.8; P = 0.005), and inflow angle (145 +/- 27 vs. 114 +/- 27 ; OR, 2.8; 95% CI, 1.1-7.2; P = 0.031). Bifurcation location (P = 0.031) and larger aneurysm size (P < 0.001) were confirmed as independent characteristics for lobulation in the RIA group. Compared with regular aneurysms, lobulated UIAs were more often allocated to treatment (86.6% vs. 60.3%; P < 0.001) and treated by microsurgical clipping (39.4% vs. 16.4%; P = 0.002). CONCLUSIONS: Bifurcation location, an increased aneurysm size, and a straighter aneurysm inflow angle are independently associated with lobulated aneurysms.
Item Type: | Journal Article | ||||||||||||||||||||||||||||||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-129747 | ||||||||||||||||||||||||||||||||||||||||||||||||
DOI: | 10.1016/j.wneu.2019.07.163 | ||||||||||||||||||||||||||||||||||||||||||||||||
Journal or Publication Title: | World Neurosurg. | ||||||||||||||||||||||||||||||||||||||||||||||||
Volume: | 131 | ||||||||||||||||||||||||||||||||||||||||||||||||
Page Range: | S. E353 - 9 | ||||||||||||||||||||||||||||||||||||||||||||||||
Date: | 2019 | ||||||||||||||||||||||||||||||||||||||||||||||||
Publisher: | ELSEVIER SCIENCE INC | ||||||||||||||||||||||||||||||||||||||||||||||||
Place of Publication: | NEW YORK | ||||||||||||||||||||||||||||||||||||||||||||||||
ISSN: | 1878-8769 | ||||||||||||||||||||||||||||||||||||||||||||||||
Language: | English | ||||||||||||||||||||||||||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||||||||||||||||||||||||||
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Refereed: | Yes | ||||||||||||||||||||||||||||||||||||||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/12974 |
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