Universität zu Köln

Hokamp, Nils Grosse, Gilkeson, R., Jordan, M. K., Laukamp, K. R., Neuhaus, Victor-Frederick, Haneder, S., Halliburton, S. S. and Gupta, A. (2019). Virtual monoenergetic images from spectral detector CT as a surrogate for conventional CT images: Unaltered attenuation characteristics with reduced image noise. Eur. J. Radiol., 117. S. 49 - 56. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-7727

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Abstract

Objective: This study aimed to identify the energy level of virtual monoenergetic images (VMI) that closest represents conventional images (CI) in order to demonstrate that these images provide improved image quality in terms of noise and Signal-to-noise ratio (SD/SNR) while attenuation values (HU) remain unaltered as compared to CI. Methods: 60 and 30 patients with contrast-enhanced (CE) and non-enhanced (NCE) spectral detector CT (SDCT) of the abdomen were included in this retrospective, IRB-approved study. CI and VMI of 66-74 keV as well as quantitative iodine maps were reconstructed (Q-IodMap). Two regions of interest were placed in each: pulmonary trunk, abdominal aorta, portal vein, liver, pancreas, renal cortex left/right, psoas muscle, (filled) bladder and subcutaneous fat. For each reconstruction, HU and SD were averaged. Delta HU and SNR (SNR = HU/SD) were calculated. Q-IodMap were considered as confounder for Delta HU. In addition, two radiologists compared VMI of 72 keV and CI in a forced-choice approach regarding image quality. Results: In NCE studies, no significant differences for any region was found. In CE studies, VMI72keV images showed lowest Delta HU (HUliver CI/VMI72keV: 104 +/- 18/103 +/- 17, p >= 0.05). Iodine containing voxels as indicated by Q-IodMap resulted in an over- and underestimation of attenuation in lower and higher VMI energies, respectively. Image noise was lower in VMI images (e.g. muscle: CI/VMI72keV: 15.3 +/- 3.3/12.3 +/- 2.9 HU, p <= 0.05). Hence, SNR was significantly higher in VMI72keV compared to CI (e.g. liver 3.8 +/- 0.6 vs 3.0 +/- 0.8, p <= 0.05). In visual analysis, VMI72keV were preferred over CI at all times. Conclusions: VMI72keV show improved SD/SNR characteristics while the attenuation remains unaltered as compared to CI.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Gilkeson, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jordan, M. K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Laukamp, K. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Neuhaus, Victor-Frederick UNSPECIFIED UNSPECIFIED UNSPECIFIED Haneder, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Halliburton, S. S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gupta, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-134030
DOI:	10.1016/j.ejrad.2019.05.019
Journal or Publication Title:	Eur. J. Radiol.
Volume:	117
Page Range:	S. 49 - 56
Date:	2019
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	1872-7727
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DUAL-ENERGY CT; COMPUTED-TOMOGRAPHY; WINDOW SETTINGS; QUANTIFICATION; RECONSTRUCTION; OPTIMIZATION; REDUCTION; ACCURACY Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13403