Iwersen-Bergmann, S., Lehmann, S., Heinemann, A., Schroeder, C., Mueller, A., Jungen, H., Andresen-Streichert, H., Pueschel, K., Vidal, C. and Mercer-Chalmers-Bender, K. (2019). Mass poisoning with NPS: 2C-E and Bromo-DragonFly. Int. J. Legal Med., 133 (1). S. 123 - 130. NEW YORK: SPRINGER. ISSN 1437-1596

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Abstract

BackgroundReports of intoxications with new psychoactive substances (NPS) mostly involve young people, as they are the main consumers of these types of drugs. This report centers on a case that was unusual due to it being a mass-poisoning event involving middle-aged individuals who had consumed a combination of the two different new psychoactive drugs 2,5-dimethoxy-4-ethylphenethylamine (2C-E) and 1-(8-bromofuro[2,3-f][1]benzofuran-4-yl)-2-propanamine (Bromo-DragonFly, BDF).Case historyThe mass poisoning of 29 individuals (24-56years old) resulted in their admission to six different hospitals with severe symptoms of intoxication. All symptoms manifested after consumption of an unknown drug formulation around lunchtime during an esoteric weekend seminar.InvestigationUrine (n=11) and blood samples (n=29), collected from the 29 individuals for police investigation, were analyzed with immunochemical techniques, GC/MS and LC-MS/MS. 2C-E was confirmed in seven urine samples, but not in blood. BDF was confirmed in all urine samples, and in 17 blood samples. The blood samples exhibited BDF concentrations between ca. 0.6 and ca. 2.0g/L, while urine concentrations of BDF ranged from ca. 1.6 to 35g/L. The concentration of 2C-E in urine was found to be between ca. 1.5 and 183g/L. All patients made a complete recovery, although some had required mechanical ventilation.ConclusionThe investigation and the presentation of this case illustrates not only mass intoxication with 2C-E and BDF, with corresponding blood and urine concentrations, but also the necessity of collecting urine samples in cases where NPS-consumption is suspected, in order to improve the chances of analytical detection.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Iwersen-Bergmann, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lehmann, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heinemann, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroeder, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mueller, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jungen, H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Andresen-Streichert, H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pueschel, K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vidal, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mercer-Chalmers-Bender, K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-139951
DOI: 10.1007/s00414-018-1882-9
Journal or Publication Title: Int. J. Legal Med.
Volume: 133
Number: 1
Page Range: S. 123 - 130
Date: 2019
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1437-1596
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SERIES; DRUGSMultiple languages
Medicine, LegalMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/13995

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