Universität zu Köln

Heidenreich, Axel, Paffenholz, Pia, Nestler, Tim and Pfister, David (2019). Management of residual masses in testicular germ cell tumors. Expert Rev. Anticancer Ther, 19 (4). S. 291 - 301. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-8328

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Abstract

Introduction: About 50% of all patients with advanced testicular cancer demonstrate residual retroperitoneal or extraretroperitoneal masses. About two thirds of the masses harbour necrosis/fibrosis only whereas as about 10% and 40% harbour vital cancer or teratoma. Appropriate therapy will result in a high cure rate if performed properly. Areas covered: This review article covers the indication, the surgical technique and the oncological outcome of PC-RPLND and resection of extraretroperitoneal residual masses following chemotherapy in patients with advanced testis cancer. Expert commentary: Postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) plays an integral part of the multimodality treatment in patients with advanced testicular germ cell tumours. Patients with nonseminomas, residual masses < 1cm and good prognosis can undergo active surveillance. In all other cases, PC-RPLND with or without resection of adjacent organs needs to be performed for curative intent. PC-RPLND requires a complex surgical approach and should be performed in experienced, tertiary referral centres only.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Heidenreich, Axel UNSPECIFIED UNSPECIFIED UNSPECIFIED Paffenholz, Pia UNSPECIFIED UNSPECIFIED UNSPECIFIED Nestler, Tim UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfister, David UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-151130
DOI:	10.1080/14737140.2019.1580146
Journal or Publication Title:	Expert Rev. Anticancer Ther
Volume:	19
Number:	4
Page Range:	S. 291 - 301
Date:	2019
Publisher:	TAYLOR & FRANCIS LTD
Place of Publication:	ABINGDON
ISSN:	1744-8328
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LYMPH-NODE DISSECTION; RETROPERITONEAL LYMPHADENECTOMY; ADVANCED SEMINOMA; POSTCHEMOTHERAPY SEMINOMA; CONSENSUS CONFERENCE; BRAIN METASTASIS; LIVER METASTASES; SALVAGE SURGERY; VIABLE TUMOR; CHEMOTHERAPY Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15113