Universität zu Köln

Mor, Joel M., Rokohl, Alexander C., Koch, Konrad R. and Heindl, Ludwig M. (2019). Sentinel lymph node biopsy in the management of conjunctival melanoma: current insights. Clin. Ophthalmol., 13. S. 1297 - 1303. ALBANY: DOVE MEDICAL PRESS LTD. ISSN 1177-5483

Full text not available from this repository.

Abstract

Purpose: To evaluate the role of sentinel lymph node biopsy (SLNB) in conjunctival melanoma (CM). Methods: This article provides a review of the literature from PUBMED. Results: Data on SLNB in the management of CM are scarce and only two relatively large cohorts have been reported. Although indication criteria for SLNB vary slightly, positive findings can be expected in 11%-13% of CM cases, including small tumors. False negative SLNB findings are rare (< 10%). Failure to identify SLNB has been attributed to the surgical learning curve and recurrent tumors with scar tissue impeding spread of the tracer material. Reported 5-year survival rate following CM management including SLNB, is up to 79%, but there are no comparative cohort studies proving the assumed benefit. Adverse events reported were non-severe and transient. Conclusion: Patients can potentially benefit from SLNB and the procedure can be offered to eligible patients. However, there is not enough evidence to support SLNB as a mandatory part of CM management.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mor, Joel M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rokohl, Alexander C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Koch, Konrad R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-160814
DOI:	10.2147/OPTH.S187364
Journal or Publication Title:	Clin. Ophthalmol.
Volume:	13
Page Range:	S. 1297 - 1303
Date:	2019
Publisher:	DOVE MEDICAL PRESS LTD
Place of Publication:	ALBANY
ISSN:	1177-5483
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TUMOR-ASSOCIATED LYMPHANGIOGENESIS; MALIGNANT-MELANOMA; FOLLOW-UP; METASTASIS; EXPERIENCE; SURVIVAL; THERAPY Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/16081