Gebauer, F., Damanakis, A. I. and Bruns, C. (2018). Oligometastasis in pancreatic cancer. Current state of knowledge and spectrum of local therapy. Chirurg, 89 (7). S. 510 - 516. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0385
Full text not available from this repository.Abstract
Several case series reported results of surgical resection in patients with pancreatic ductal adenocarcinoma in a metastasized stage. A summarized overview of the current state of knowledge and a summary of the results of currently available studies. A systematic search was carried out in MEDLINE and PubMed with respect to metastasized pancreatic cancer and surgical resection. The evidence level for surgical resection in the metastasized stage is weak and so far no prospective trials are available. The largest single-arm trial included 85 patients with hepatic metastasis. In cases of hepatic oligometastasis an overall survival of 11-14 months was observed. In the presence of pulmonary metastasis, overall survival seems to be prolonged compared to intra-abdominal metastasis, although the evidence level is relatively weak. According to the available results, a general recommendation for surgical resection in a metastasized stage cannot be given; however, the results show a possible benefit for some well-selected patient subgroups. Prospective trials must validate these data and investigate the use of combined surgical and systemic treatments in the case of resectable metastatic pancreatic cancer.
Item Type: | Journal Article | ||||||||||||||||
Creators: |
|
||||||||||||||||
URN: | urn:nbn:de:hbz:38-181776 | ||||||||||||||||
DOI: | 10.1007/s00104-018-0626-1 | ||||||||||||||||
Journal or Publication Title: | Chirurg | ||||||||||||||||
Volume: | 89 | ||||||||||||||||
Number: | 7 | ||||||||||||||||
Page Range: | S. 510 - 516 | ||||||||||||||||
Date: | 2018 | ||||||||||||||||
Publisher: | SPRINGER HEIDELBERG | ||||||||||||||||
Place of Publication: | HEIDELBERG | ||||||||||||||||
ISSN: | 1433-0385 | ||||||||||||||||
Language: | German | ||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||
Subjects: | no entry | ||||||||||||||||
Uncontrolled Keywords: |
|
||||||||||||||||
Refereed: | Yes | ||||||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/18177 |
Downloads
Downloads per month over past year
Altmetric
Export
Actions (login required)
View Item |