Huntgeburth, Michael, Neidenbach, Rhoia Clara, von Kodolitsch, Yskert and Kaemmerer, Harald (2018). Genetic Aortic Syndromes - Recommendations for Cardiologists in Practice and Clinic. Aktuelle Kardiol., 7 (3). S. 220 - 231. STUTTGART: GEORG THIEME VERLAG KG. ISSN 2193-5211

Full text not available from this repository.

Abstract

Dilatation of the aorta is a condition. Knowledge of the underlying causes and mechanisms allows adequate diagnosis and guidance of patients. Genetically determined aortic diseases are associated with increased risk for aortic complication (dissection/rupture). The underlying conditions include syndromic (e.g. Marfan-, Loeys-Dietz-, vascular Ehlers-Danlos-Syndrome) and non-syndromic conditions (e.g. bicuspid aortic valve - BAV, aortic coarctation, complex congenital heart diseases, familial thoracic aortic aneurysm - FTAA, dissections FTAAD). Family history, clinical investigation, imaging and genetic testing are used for diagnosis. A precise diagnosis and risk stratifying for aortic complications are crucial for the prognosis of these patients. The management includes modifications in lifestyle (e.g. physical stress in sport and work), a medical prophylaxis of aortic growth (reduction of wall stress), an elective aortic replacement and regular follow-up examinations. Due to the complexity of aortopathies, a multi-disciplinary care is required. Additionally, a family screening of all first-degree family members is necessary to identify others at risk.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Huntgeburth, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Neidenbach, Rhoia ClaraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
von Kodolitsch, YskertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaemmerer, HaraldUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-184283
DOI: 10.1055/a-0626-6961
Journal or Publication Title: Aktuelle Kardiol.
Volume: 7
Number: 3
Page Range: S. 220 - 231
Date: 2018
Publisher: GEORG THIEME VERLAG KG
Place of Publication: STUTTGART
ISSN: 2193-5211
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
CONGENITAL HEART-DISEASE; MARFAN-SYNDROME; MANAGEMENT; ADULTS; ASSOCIATION; GUIDELINES; DISSECTION; SCOREMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/18428

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item