Universität zu Köln

Haenicke, Joachim, Yamagata, Nobuhiro, Zwaka, Hanna, Nawrot, Martin and Menzel, Randolf (2018). Neural Correlates of Odor Learning in the Presynaptic Microglomerular Circuitry in the Honeybee Mushroom Body Calyx. eNeuro, 5 (3). WASHINGTON: SOC NEUROSCIENCE. ISSN 2373-2822

Full text not available from this repository.

Abstract

The mushroom body (MB) in insects is known as a major center for associative learning and memory, although exact locations for the correlating memory traces remain to be elucidated. Here, we asked whether presynaptic boutons of olfactory projection neurons (PNs) in the main input site of the MB undergo neuronal plasticity during classical odor-reward conditioning and correlate with the conditioned behavior. We simultaneously measured Ca2+ responses in the boutons and conditioned behavioral responses to learned odors in honeybees. We found that the absolute amount of the neural change for the rewarded but not for the unrewarded odor was correlated with the behavioral learning rate across individuals. The temporal profile of the induced changes matched with odor response dynamics of the MB-associated inhibitory neurons, suggestive of activity modulation of boutons by this neural class. We hypothesize the circuit-specific neural plasticity relates to the learned value of the stimulus and underlies the conditioned behavior of the bees.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Haenicke, Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED Yamagata, Nobuhiro UNSPECIFIED UNSPECIFIED UNSPECIFIED Zwaka, Hanna UNSPECIFIED UNSPECIFIED UNSPECIFIED Nawrot, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Menzel, Randolf UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-187349
DOI:	10.1523/ENEURO.0128-18.2018
Journal or Publication Title:	eNeuro
Volume:	5
Number:	3
Date:	2018
Publisher:	SOC NEUROSCIENCE
Place of Publication:	WASHINGTON
ISSN:	2373-2822
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PROBOSCIS EXTENSION RESPONSE; EXTRINSIC NEURONS; IDENTIFIED NEURON; FEEDBACK NEURONS; APIS-MELLIFERA; MEMORY TRACES; PLASTICITY; BRAIN; REPRESENTATIONS; DYNAMICS Multiple languages Neurosciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18734