Universität zu Köln

Wunram, Heidrun Lioba, Hamacher, Stefanie ORCID: 0000-0003-2158-9101, Hellmich, Martin, Volk, Maxi, Jaenicke, Franziska, Reinhard, Franziska, Bloch, Wilhelm, Zimmer, Philipp, Graf, Christine, Schoenau, Eckhard, Lehmkuhl, Gerd, Bender, Stephan and Fricke, Oliver (2018). Whole body vibration added to treatment as usual is effective in adolescents with depression: a partly randomized, three-armed clinical trial in inpatients. Eur. Child Adolesc. Psych., 27 (5). S. 645 - 663. NEW YORK: SPRINGER. ISSN 1435-165X

Full text not available from this repository.

Abstract

There is growing evidence for the effectiveness of exercise in the treatment of adult major depression. With regard to adolescents, clinical trials are scarce. Due to the inherent symptoms of depression (lack of energy, low motivation to exercise), endurance training forms could be too demanding especially in the first weeks of treatment. We hypothesized that an easy-to-perform passive muscular training on a whole body vibration (WBV) device has equal anti-depressive effects compared to a cardiovascular training, both administered as add-ons to treatment as usual (TAU). Secondly, we presumed that both exercise interventions would be superior in their response, compared to TAU. In 2 years 64 medication-na < ve depressed inpatients aged 13-18, were included. Both exercise groups fulfilled a supervised vigorous training for 6 weeks. Depressive symptoms were assessed by self-report (Depressions Inventar fur Kinder und Jugendliche-DIKJ) before intervention and after weeks 6, 14 and 26. Compared to TAU, both groups responded earlier and more strongly measured by DIKJ scores, showing a trend for the WBV group after week 6 (p = 0.082). The decrease became statistically significant for both intervention groups after week 26 (p = 0.037 for ergometer and p = 0.042 for WBV). Remission rates amounted to 39.7% after week 6 and 66% after week 26, compared to 25% after week 26 in TAU. These results provide qualified support for the effectiveness of exercise as add-on treatment for medication-na < ve depressed adolescents. The present results are limited by the not randomized control group.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Wunram, Heidrun Lioba UNSPECIFIED UNSPECIFIED UNSPECIFIED Hamacher, Stefanie UNSPECIFIED orcid.org/0000-0003-2158-9101 UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Volk, Maxi UNSPECIFIED UNSPECIFIED UNSPECIFIED Jaenicke, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Reinhard, Franziska UNSPECIFIED UNSPECIFIED UNSPECIFIED Bloch, Wilhelm UNSPECIFIED UNSPECIFIED UNSPECIFIED Zimmer, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Graf, Christine UNSPECIFIED UNSPECIFIED UNSPECIFIED Schoenau, Eckhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Lehmkuhl, Gerd UNSPECIFIED UNSPECIFIED UNSPECIFIED Bender, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Fricke, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-187723
DOI:	10.1007/s00787-017-1071-2
Journal or Publication Title:	Eur. Child Adolesc. Psych.
Volume:	27
Number:	5
Page Range:	S. 645 - 663
Date:	2018
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1435-165X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BDNF VAL66MET POLYMORPHISM; PHYSICAL-ACTIVITY; MENTAL-HEALTH; EXERCISE; CHILDREN; SYMPTOMS; ANXIETY; FLUOXETINE; ASSOCIATION; SUICIDALITY Multiple languages Psychology, Developmental; Pediatrics; Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18772