Herkenrath, Simon Dominik, Treml, Marcel, Priegnitz, Christina, Galetke, Wolfgang and Randerath, Winfried J. (2018). Effects of respiratory muscle training (RMT) in patients with mild to moderate obstructive sleep apnea (OSA). Sleep Breath., 22 (2). S. 323 - 329. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1522-1709

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Abstract

Purpose Different forms of training focusing on the muscles of the upper airways showed limited effects on obstructive sleep apnea (OSA) and/or snoring. We investigated the effect of generalized respiratory muscle training (RMT) in lean patients with mild to moderate OSA. Methods Nine male subjects (52.0 +/- 10.8 years, BMI 29.1 +/- 2.1 kg/m(2)) with obstructive sleep apnea (apneahypopnea index (AHI) 9-29) participated in an open, singlearm pilot study. After a 1-week build-up phase, patients underwent 4 weeks of normocapnic hyperpnea RMT five times a week for 30 min each. The initial and final measurements comprised polysomnography, pulmonary function tests, Epworth sleepiness scale (ESS), and SF-36 questionnaire (quality of life (QoL) self-assessment). The investigational site was a university-affiliated hospital for pulmonary diseases and sleep medicine, Solingen/Germany. Results Patients trained effectively, seen by a significant (p < 0.01) increase of breathing frequency (23.3 +/- 1.5/min vs. 30.6 +/- 2.9 / min) and minute volume (81.2 +/- 13.7 L vs. 109.1 +/- 21.9 L). AHI, snoring and ESS remained unchanged after training. QoL as measured by SF-36 significantly (p < 0.05) improved after the training in the subscales Bbodily pain'' (79 +/- 21 vs. 90 +/- 12) and Bchange of health'' (3.1 +/- 0.3 vs. 2.4 +/- 0.5). Conclusions There is no evidence that AHI, pulmonary function or daytime sleepiness are affected by 5 weeks of RMT. Nevertheless, there is an improvement of parameters of quality of life.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Herkenrath, Simon DominikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Treml, MarcelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Priegnitz, ChristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Galetke, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Randerath, Winfried J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-188209
DOI: 10.1007/s11325-017-1582-6
Journal or Publication Title: Sleep Breath.
Volume: 22
Number: 2
Page Range: S. 323 - 329
Date: 2018
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1522-1709
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
UPPER-AIRWAY STIMULATION; ADHERENCE; DEVICE; CPAPMultiple languages
Clinical Neurology; Respiratory SystemMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/18820

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