Buser, Genevieve L., Cassidy, P. Maureen, Cunningham, Margaret C., Rudin, Susan, Hujer, Andrea M., Vega, Robert, Furuno, Jon P., Marshall, Steven H., Higgins, Paul G. ORCID: 0000-0001-8677-9454, Jacobs, Michael R., Wright, Meredith S., Adams, Mark D., Bonomo, Robert A., Pfeiffer, Christopher D. and Beldavs, Zintars G. (2017). Failure to Communicate: Transmission of Extensively Drug-Resistant bla(OXA-237)-Containing Acinetobacter baumannii-Multiple Facilities in Oregon, 2012-2014. Infect. Control Hosp. Epidemiol., 38 (11). S. 1335 - 1342. NEW YORK: CAMBRIDGE UNIV PRESS. ISSN 1559-6834

Full text not available from this repository.

Abstract

OBJECTIVE To determine the scope, source, and mode of transmission of a multifacility outbreak of extensively drug-resistant (XDR) Acinetobacter baumannii. DESIGN Outbreak investigation. SETTING AND PARTICIPANTS Residents and patients in skilled nursing facilities, long-term acute-care hospital, and acute-care hospitals. METHODS A case was defined as the incident isolate from clinical or surveillance cultures of XDR Acinetobacter baumannii resistant to imipenem or meropenem and nonsusceptible to all but 1 or 2 antibiotic classes in a patient in an Oregon healthcare facility during January 2012-December 2014. We queried clinical laboratories, reviewed medical records, oversaw patient and environmental surveillance surveys at 2 facilities, and recommended interventions. Pulsed-field gel electrophoresis (PFGE) and molecular analysis were performed. RESULTS We identified 21 cases, highly related by PFGE or healthcare facility exposure. Overall, 17 patients (81%) were admitted to either long-term acute-care hospital A (n=8), or skilled nursing facility A (n=8), or both (n=1) prior to XDR A. baumannii isolation. Interfacility communication of patient or resident XDR status was not performed during transfer between facilities. The rare plasmid-encoded carbapenemase gene bla(OXA-237) was present in 16 outbreak isolates. Contact precautions, chlorhexidine baths, enhanced environmental cleaning, and interfacility communication were implemented for cases to halt transmission. CONCLUSIONS Interfacility transmission of XDR A. baumannii carrying the rare bla(OXA-237) was facilitated by transfer of affected patients without communication to receiving facilities. Infect Control Hosp Epidemiol 2017;38:1335-1341

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Buser, Genevieve L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cassidy, P. MaureenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cunningham, Margaret C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rudin, SusanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hujer, Andrea M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vega, RobertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Furuno, Jon P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marshall, Steven H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Higgins, Paul G.UNSPECIFIEDorcid.org/0000-0001-8677-9454UNSPECIFIED
Jacobs, Michael R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wright, Meredith S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Adams, Mark D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bonomo, Robert A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfeiffer, Christopher D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beldavs, Zintars G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-213430
DOI: 10.1017/ice.2017.189
Journal or Publication Title: Infect. Control Hosp. Epidemiol.
Volume: 38
Number: 11
Page Range: S. 1335 - 1342
Date: 2017
Publisher: CAMBRIDGE UNIV PRESS
Place of Publication: NEW YORK
ISSN: 1559-6834
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MOLECULAR EPIDEMIOLOGY; GLOBAL SPREAD; OUTBREAK; CARE; ENTEROBACTERIACEAE; SURVEILLANCE; PREVENTION; INFECTIONMultiple languages
Public, Environmental & Occupational Health; Infectious DiseasesMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/21343

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item