Eckes, Beate, Wang, Fang, Moinzadeh, Pia, Hunzelmann, Nicolas and Krieg, Thomas (2017). Pathophysiological Mechanisms in Sclerosing Skin Diseases. Front. Med., 4. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-858X
Full text not available from this repository.Abstract
Sclerosing skin diseases represent a large number of distinct disease entities, which include systemic sclerosis, localized scleroderma, and scleredema adultorum. These pathologies have a common clinical appearance and share histological features. However, the specific interplay between cytokines and growth factors, which activate different mesenchymal cell populations and production of different extracellular matrix components, determines the biomechanical properties of the skin and the clinical features of each disease. A better understanding of the mechanisms underlying these events is prerequisite for developing novel targeted therapeutic approaches.
| Item Type: | Journal Article | ||||||||||||||||||||||||
| Creators: |
|
||||||||||||||||||||||||
| URN: | urn:nbn:de:hbz:38-221652 | ||||||||||||||||||||||||
| DOI: | 10.3389/fmed.2017.00120 | ||||||||||||||||||||||||
| Journal or Publication Title: | Front. Med. | ||||||||||||||||||||||||
| Volume: | 4 | ||||||||||||||||||||||||
| Date: | 2017 | ||||||||||||||||||||||||
| Publisher: | FRONTIERS MEDIA SA | ||||||||||||||||||||||||
| Place of Publication: | LAUSANNE | ||||||||||||||||||||||||
| ISSN: | 2296-858X | ||||||||||||||||||||||||
| Language: | English | ||||||||||||||||||||||||
| Faculty: | Unspecified | ||||||||||||||||||||||||
| Divisions: | Unspecified | ||||||||||||||||||||||||
| Subjects: | no entry | ||||||||||||||||||||||||
| Uncontrolled Keywords: |
|
||||||||||||||||||||||||
| Refereed: | Yes | ||||||||||||||||||||||||
| URI: | http://kups.ub.uni-koeln.de/id/eprint/22165 |
Downloads
Downloads per month over past year
Altmetric
Export
Actions (login required)
 |
View Item |