Universität zu Köln

Macherey, S., Kauffmann, C., Heidenreich, A., Doerr, F., Wahlers, T. and Hekmat, K. (2017). Pulmonary metastasectomy in renal cell carcinoma. Urologe, 56 (8). S. 1025 - 1031. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0563

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Abstract

In patients with isolated meta- or synchronous pulmonary metastases from renal cell cancer, lung metastasectomy could be an appropriate treatment option after successful treatment of primary cancer. Presentation of lung metastasectomy as a treatment option in patients with pulmonary metastatic renal cell cancer and the postoperative outcome. Description of alternative treatment modalities focusing on targeted therapies. Systematical literature research and qualitative analysis of studies on patients undergoing lung metastasectomy after primary nephrectomy published since 01 January 2000. We assessed operative findings, survival data, and prognostic factors. Pulmonary metastasectomy results in a median postmetastasectomy survival of 26-94 months. The 5aEuroyear survival rates vary between 33 and 58%. The patients' prognosis depends on a prolonged disease-free interval and complete resection of all suspected metastases. In particular, number and location of lung metastases should play a minor role for the indication for lung metastasectomy. Pulmonary metastasectomy should be considered the treatment of choice in selected patients with successfully resected primary cancer showing no evidence of extrapulmonary metastases and having guaranteed operability and complete resection.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Macherey, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kauffmann, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heidenreich, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Doerr, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hekmat, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-222967
DOI:	10.1007/s00120-017-0353-0
Journal or Publication Title:	Urologe
Volume:	56
Number:	8
Page Range:	S. 1025 - 1031
Date:	2017
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-0563
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LYMPH-NODE DISSECTION; LONG-TERM SURVIVAL; PROGNOSTIC-FACTORS; SURGICAL-TREATMENT; LUNG METASTASES; THERAPY; CANCER; RESECTION; CHEMOTHERAPY; EXPERIENCE Multiple languages Urology & Nephrology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22296