Universität zu Köln

Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Berlth, Felix ORCID: 0000-0002-3780-0728, Plum, Patrick Sven, Herbold, Till, Alakus, Hakan, Kleinert, Robert, Moenig, Stefan Paul, Bruns, Christiane Josephine, Hoelscher, Arnulf Heinrich and Meyer, Hans-Joachim (2017). Gastric cancer treatment in the world: Germany. Transl. Gastroenterol. Hepatol., 2. SHEUNG WAN: AME PUBL CO. ISSN 2415-1289

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Abstract

Epidemiologically, around 15,500 persons per year contract gastric cancer with continuously decreasing incidence and a 5-year survival rate of only 30% to 35%. Contrary to the Asian countries, there are no prevention programs for gastric cancer in Germany, which leads to the disease frequently being diagnosed in locally advanced stages and predominantly being treated with multimodal therapy concepts. Complete (R0) resection is the therapy of choice for resectable gastric cancer. Special forms of gastric cancer that are limited to the mucosa can be endoscopically resected with a curative intent. Systematic D2 lymphadenectomy (LAD) plays a decisive role in the management of local advanced tumors because it significantly contributes to the reduction of tumor-related death and both local and regional relapse rates. Perioperative chemotherapy improves prognosis in the advanced stages, whereas palliative chemotherapy is normally indicated for metastatic diseases. Standardized resection procedures and the use of individualized multimodal therapy concepts have led to improvement in the 5-year survival rate.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Chon, Seung-Hun UNSPECIFIED orcid.org/0000-0002-8923-6428 UNSPECIFIED Berlth, Felix UNSPECIFIED orcid.org/0000-0002-3780-0728 UNSPECIFIED Plum, Patrick Sven UNSPECIFIED UNSPECIFIED UNSPECIFIED Herbold, Till UNSPECIFIED UNSPECIFIED UNSPECIFIED Alakus, Hakan UNSPECIFIED UNSPECIFIED UNSPECIFIED Kleinert, Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED Moenig, Stefan Paul UNSPECIFIED UNSPECIFIED UNSPECIFIED Bruns, Christiane Josephine UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoelscher, Arnulf Heinrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Meyer, Hans-Joachim UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-231541
DOI:	10.21037/tgh.2017.05.07
Journal or Publication Title:	Transl. Gastroenterol. Hepatol.
Volume:	2
Date:	2017
Publisher:	AME PUBL CO
Place of Publication:	SHEUNG WAN
ISSN:	2415-1289
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PERIOPERATIVE CHEMOTHERAPY; GASTROESOPHAGEAL JUNCTION; LAPAROSCOPIC GASTRECTOMY; ENDOSCOPIC RESECTION; SURGERY; MULTICENTER; TRIAL; ADENOCARCINOMA; DIAGNOSIS; OUTCOMES Multiple languages Gastroenterology & Hepatology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23154