Hoffmann, Michael, Lehmann, Wolfgang, Schroeder, Malte, Cramer, Christopher, Grossterlinden, Lars G., Rueger, Johannes M. and Lefering, Rolf (2017). Prospective evaluation of the Eppendorf-Cologne Scale. Eur. J. Emerg. Med., 24 (2). S. 120 - 126. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-5695

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Abstract

ObjectivesEarly diagnosis of traumatic brain injury and reliable prediction of outcome are essential for determining treatment strategies and allocating resources. This study re-evaluates the Eppendorf-Cologne Scale (ECS) and its predictive accuracy for outcome compared with the Glasgow Coma Scale (GCS).MethodsA prospective cohort analysis of severely injured trauma patients registered in the Trauma Registry of the German Society for Trauma Surgery from 2012-2013 was carried out. Only directly admitted patients alive on admission with complete data on GCS, ECS and outcome in terms of survival to hospital discharge or death were included. The predictive accuracy in terms of the outcome of the ECS and the GCS was modelled using area under the receiver operating characteristic (AUROC) curve analysis.ResultsA total of 17616 patients fulfilled the study inclusion criteria. The ECS outmatched the predictive accuracy of the GCS for outcome (AUROC, 0.853, 95% confidence interval, 0.831-0.854; and AUROC 0.836; 95% confidence interval, 0.825-0.848, respectively; P=0.062). An ECS score of 8 was associated with a 25-fold higher mortality compared with an ECS score of 0. Patients who had an ECS score of 8 had a 1.5-fold higher mortality compared with patients allocated a GCS score of 3.ConclusionThe ECS shows a higher accuracy for prediction of outcome compared with the GCS and enables further differentiation within the critical GCS 3 collective.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Hoffmann, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lehmann, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroeder, MalteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cramer, ChristopherUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grossterlinden, Lars G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rueger, Johannes M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lefering, RolfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-235557
DOI: 10.1097/MEJ.0000000000000306
Journal or Publication Title: Eur. J. Emerg. Med.
Volume: 24
Number: 2
Page Range: S. 120 - 126
Date: 2017
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Place of Publication: PHILADELPHIA
ISSN: 1473-5695
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
GLASGOW COMA SCALE; TRAUMATIC BRAIN-INJURY; PUPIL REACTIVITY; SCORE; PREDICTION; MORTALITYMultiple languages
Emergency MedicineMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/23555

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