Universität zu Köln

Hentrich, Marcus and Pfister, David (2017). HIV-Aspociated Urogenital Malignancies. Oncol. Res. Treat., 40 (3). S. 106 - 113. BASEL: KARGER. ISSN 2296-5262

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Abstract

Non-AIDS-defining malignancies (NADM) are a leading cause of morbidity and mortality for HIV-infected subjects. The risk of testicular germ cell cancer (GCC) and renal cell cancer is slightly increased in the setting of HIV, whereas there is a slightly decreased risk of prostate cancer and bladder cancer. As in industrialized countries the majority of people living with HIV are men, and people aged 55 and older now account for more than a quarter of perisons living with HIV, both testis and prostate cancer are assumed to occur with increased frequency in HIV-infected subjects. Overall, treatments should be theisanne as in HIV-negative patients with urogenital malignancies. Since the introduction of combination antiretroviral therapy (cART) the outcome appears to have improved due to a decrease in HIV-related deaths. HIV-infected men who are treated with standard therapies for 'GCC now have a similar cancer-free survival compared with their HIV-negative counterparts. Screening and treatment for prostate cancer should follow recommendations established for HIV-negative men. During radiotor chemotherapy patients should receive concurrent cART but the drug-drug interaction potential must be taken' into account. (C) 2017 S. Karger GmbH, Freiburg

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hentrich, Marcus UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfister, David UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-238302
DOI:	10.1159/000457130
Journal or Publication Title:	Oncol. Res. Treat.
Volume:	40
Number:	3
Page Range:	S. 106 - 113
Date:	2017
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	2296-5262
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HUMAN-IMMUNODEFICIENCY-VIRUS; GERM-CELL TUMORS; ACTIVE ANTIRETROVIRAL THERAPY; AIDS-DEFINING CANCERS; PROSTATE-CANCER; BLADDER-CARCINOMA; INFECTED PATIENTS; RADICAL PROSTATECTOMY; GENERAL-POPULATION; UNITED-STATES Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23830