Universität zu Köln

Escher, Claus M., Paracka, Lejla, Dressler, Dirk and Kollewe, Katja (2017). Botulinum toxin in the management of chronic migraine: clinical evidence and experience. Ther. Adv. Neurol. Disord., 10 (2). S. 127 - 136. LONDON: SAGE PUBLICATIONS LTD. ISSN 1756-2864

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Abstract

Chronic migraine (CM) is a severely disabling neurological condition characterized by episodes of pulsating unilateral or bilateral headache. The United States Food and Drug Administration (FDA) approved onabotulinumtoxinA (Botox (R)) for the prophylactic treatment of CM in 2010. It has been shown that onabotulinumtoxinA is effective in the reduction of headache frequency and severity in patients with CM. Treatment is well tolerated by the patients. This review reports on the history of botulinum neurotoxin (BoNT) in CM and presents the current clinical evidence for the use of onabotulinumtoxinA in the treatment of CM.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Escher, Claus M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Paracka, Lejla UNSPECIFIED UNSPECIFIED UNSPECIFIED Dressler, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED Kollewe, Katja UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-240786
DOI:	10.1177/1756285616677005
Journal or Publication Title:	Ther. Adv. Neurol. Disord.
Volume:	10
Number:	2
Page Range:	S. 127 - 136
Date:	2017
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1756-2864
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CHRONIC DAILY HEADACHE; QUALITY-OF-LIFE; PLACEBO-CONTROLLED PHASE; RANDOMIZED DOUBLE-BLIND; PROPHYLACTIC TREATMENT; EPISODIC MIGRAINEURS; MEDICATION OVERUSE; CERVICAL DYSTONIA; SUBGROUP ANALYSIS; REDUCES IMPACT Multiple languages Clinical Neurology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24078