Universität zu Köln

Qamar, M. A., Sauerbier, A., Politis, M., Carr, H., Loehrer, P. and Chaudhuri, K. Ray (2017). Presynaptic dopaminergic terminal imaging and non-motor symptoms assessment of Parkinson's disease: evidence for dopaminergic basis? npj Parkinsons Dis., 3. LONDON: NATURE PUBLISHING GROUP. ISSN 2373-8057

Full text not available from this repository.

Abstract

Parkinson's disease (PD) is now considered to be a multisystemic disorder consequent on multineuropeptide dysfunction including dopaminergic, serotonergic, cholinergic, and noradrenergic systems. This multipeptide dysfunction leads to expression of a range of non-motor symptoms now known to be integral to the concept of PD and preceding the diagnosis of motor PD. Some non-motor symptoms in PD may have a dopaminergic basis and in this review, we investigate the evidence for this based on imaging techniques using dopamine-based radioligands. To discuss non-motor symptoms we follow the classification as outlined by the validated PD non-motor symptoms scale.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Qamar, M. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sauerbier, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Politis, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Carr, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Loehrer, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Chaudhuri, K. Ray UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-242222
DOI:	10.1038/s41531-016-0006-9
Journal or Publication Title:	npj Parkinsons Dis.
Volume:	3
Date:	2017
Publisher:	NATURE PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	2373-8057
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SLEEP BEHAVIOR DISORDER; RESTLESS LEGS SYNDROME; CARDIAC SYMPATHETIC DENERVATION; IMPULSE CONTROL DISORDERS; POSITRON-EMISSION-TOMOGRAPHY; BODY-MASS INDEX; STRIATAL DOPAMINE; VISUAL HALLUCINATIONS; COGNITIVE IMPAIRMENT; DEPRESSIVE SYMPTOMS Multiple languages Neurosciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24222