Universität zu Köln

Holsten, Till, Schuster, Tobias, Grabhorn, Enke, Hero, Barbara and Fruehwald, Michael C. (2017). Liver transplantation as a potentially lifesaving measure in neuroblastoma stage 4S. Pediatr. Hematol. Oncol., 34 (1). S. 17 - 24. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1521-0669

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Abstract

Neuroblastoma (NBL) stage 4s is an incompletely understood phenomenon with variable clinical course. While the majority of patients may undergo spontaneous regression and achieve complete resolution without intensive therapy, a small proportion is at increased risk of developing secondary complications. One such situation is liver insufficiency due to diffuse metastases. We report a patient suffering from NBL 4S who required double lifesaving liver transplantation. Abdominal and respiratory complications due to hepatomegaly are crucial determinants for treatment intensity and duration in 4S NBL [1,2]. We provide an algorithm in order to facilitate the clinical decision when dealing with similar potentially life-threatening events.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Holsten, Till UNSPECIFIED UNSPECIFIED UNSPECIFIED Schuster, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Grabhorn, Enke UNSPECIFIED UNSPECIFIED UNSPECIFIED Hero, Barbara UNSPECIFIED UNSPECIFIED UNSPECIFIED Fruehwald, Michael C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-246559
DOI:	10.1080/08880018.2016.1266535
Journal or Publication Title:	Pediatr. Hematol. Oncol.
Volume:	34
Number:	1
Page Range:	S. 17 - 24
Date:	2017
Publisher:	TAYLOR & FRANCIS INC
Place of Publication:	PHILADELPHIA
ISSN:	1521-0669
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language IV-S NEUROBLASTOMA; THERAPY; NEONATE; INFANT Multiple languages Oncology; Hematology; Pediatrics Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24655