Kaasch, Achim J. and Seifert, Harald (2016). Oritavancin: a long-acting antibacterial lipoglycopeptide. Future Microbiol., 11 (7). S. 843 - 856. LONDON: FUTURE MEDICINE LTD. ISSN 1746-0921
Full text not available from this repository.Abstract
Oritavancin is a new lipoglycopeptide antibacterial agent with an exceptionally long terminal half-life and a rapid bactericidal effect. Multiple mechanisms of action lead to a broad activity against Gram-positive bacteria, such as staphylococci, streptococci and enterococci, including methicillin-resistant Staphylococcus aureus. Its long terminal half-life allows for single-dose treatment of acute bacterial skin and skin structure infections. Oritavancin was found to be safe and effective in treating acute bacterial skin and skin structure infections in adults and it is currently approved in the USA and in Europe for this indication. Unfortunately, data for other indications are lacking. Here, we review chemistry, microbiology, pharmacology, efficacy and tolerability of oritavancin.
Item Type: | Journal Article | ||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-270372 | ||||||||||||
DOI: | 10.2217/fmb-2016-0003 | ||||||||||||
Journal or Publication Title: | Future Microbiol. | ||||||||||||
Volume: | 11 | ||||||||||||
Number: | 7 | ||||||||||||
Page Range: | S. 843 - 856 | ||||||||||||
Date: | 2016 | ||||||||||||
Publisher: | FUTURE MEDICINE LTD | ||||||||||||
Place of Publication: | LONDON | ||||||||||||
ISSN: | 1746-0921 | ||||||||||||
Language: | English | ||||||||||||
Faculty: | Unspecified | ||||||||||||
Divisions: | Unspecified | ||||||||||||
Subjects: | no entry | ||||||||||||
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Refereed: | Yes | ||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/27037 |
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