Biermann, C. D., Kribs, A., Roth, B. and Tantcheva-Poor, I. (2016). Use and Cutaneous Side Effects of Skin Antiseptics in Extremely Low Birth Weight Infants - A Retrospective Survey of the German NICUs. Klinische Padiatr., 228 (4). S. 208 - 213. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3824

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Abstract

Background Nosocomial infections are a serious problem in the treatment of extremely low birth weight infants (ELBW, <1000g). In these patients, effective skin antisepsis is critical to prevent hospital-acquired infections and their sequelae. However, serious side effects of topical antiseptics have been repeatedly reported in extremely preterm infants and no agreement has been reached on the best product in this population. Therefore, we conducted a survey of the German NICUs aiming to investigate current practices and safety of topical antiseptics in ELBW neonates. Methods: We sent anonymized questionnaires to 166 German NICUs with the highest level of care. Results: Usable questionnaires were returned by 64 NICUs (39%). These NICUs had treated a total of 2130 patients with a birth weight<1000g in 2012. Octenidine without phenoxyethanol (OwPh) and Octenisept((R)) were the predominantly used skin antiseptics for intensive-care procedures. At least one skin complication was reported by 27% (n=17) of the NICUs. In 9 cases Octenisept((R)) was used, and in 6 cases octenidine was used. Conclusions: According to our knowledge, this is the first study surveying practices and safety of skin antisepsis in ELBWs in the German NICUs. Most German NICUs use octenidine, however, in different preparations. Skin complications including blistering, necrosis and scarring were seen with all octenidine products, a fact which has not been previously reported.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Biermann, C. D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kribs, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roth, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tantcheva-Poor, I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-270662
DOI: 10.1055/s-0042-104122
Journal or Publication Title: Klinische Padiatr.
Volume: 228
Number: 4
Page Range: S. 208 - 213
Date: 2016
Publisher: GEORG THIEME VERLAG KG
Place of Publication: STUTTGART
ISSN: 1439-3824
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ALCOHOL BURNS; INFECTIONS; NEONATE; CARE; PREVENTION; OCTENIDINE; IODINE; UNITSMultiple languages
PediatricsMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/27066

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