Universität zu Köln

Polidori, M. Cristina and Scholtes, Marlies (2016). Beyond and behind the fingerprints of oxidative stress in age-related diseases: Secrets of successful aging. Arch. Biochem. Biophys., 595. S. 50 - 54. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1096-0384

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Abstract

Several years after the first publication of the definition of oxidative stress by Helmut Sies, this topic is still focus of a large body of attention and research in the field of aging, neurodegeneration and disease prevention. The conduction of clinical and epidemiological research without a solid biochemical rationale has led to largely frustrating results without being able to disprove the oxidative stress hypothesis. The present work is dedicated to Helmut Sies and describes the successful scientific approach to bench-to-bedside (-to-behavior) oxidative stress clinical research. (C) 2015 Elsevier Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Polidori, M. Cristina UNSPECIFIED UNSPECIFIED UNSPECIFIED Scholtes, Marlies UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-278906
DOI:	10.1016/j.abb.2015.06.021
Journal or Publication Title:	Arch. Biochem. Biophys.
Volume:	595
Page Range:	S. 50 - 54
Date:	2016
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1096-0384
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MILD COGNITIVE IMPAIRMENT; LIPOPHILIC ANTIOXIDANTS; PLASMA-LEVELS; LIPID-PEROXIDATION; HUMAN SERUM; ALPHA-CEHC; VITAMIN-C; MALONDIALDEHYDE; HYDROPEROXIDES Multiple languages Biochemistry & Molecular Biology; Biophysics Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/27890