Universität zu Köln

Barbui, Tiziano, Thiele, Juergen, Vannucchi, Alessandro M. and Tefferi, Ayalew (2016). Myeloproliferative neoplasms: Morphology and clinical practice. Am. J. Hematol., 91 (4). S. 430 - 434. HOBOKEN: WILEY. ISSN 1096-8652

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Abstract

In myeloproliferative neoplasms (MPNs), controversy persists regarding the usefulness and reproducibility of bone marrow (BM) features. Disagreements concerning the WHO classification are mainly focused on the discrimination between essential thrombocythemia (ET) and prefibrotic/early primary myelofibrosis (prePMF) and prodromal polycythemia vera (PV). Criticism mostly refers to lack of standardization of distinctive BM features precluding correct morphological pattern recognition. The distinction between WHO-defined ET and prePMF is not trivial because outcome is significantly worse in prePMF. Morphology was generally considered to be non-specific for the diagnosis of PV. Recent studies have revealed under-diagnosis of morphologically and biologically consistent PV. Am. J. Hematol. 91:430-433, 2016. (c) 2015 Wiley Periodicals, Inc.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Barbui, Tiziano UNSPECIFIED UNSPECIFIED UNSPECIFIED Thiele, Juergen UNSPECIFIED UNSPECIFIED UNSPECIFIED Vannucchi, Alessandro M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Tefferi, Ayalew UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-280002
DOI:	10.1002/ajh.24288
Journal or Publication Title:	Am. J. Hematol.
Volume:	91
Number:	4
Page Range:	S. 430 - 434
Date:	2016
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1096-8652
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BONE-MARROW FIBROSIS; CHRONIC IDIOPATHIC MYELOFIBROSIS; INTERNATIONAL WORKING GROUP; ESSENTIAL THROMBOCYTHEMIA; POLYCYTHEMIA-VERA; REFRACTORY-ANEMIA; RINGED SIDEROBLASTS; DIAGNOSTIC-CRITERIA; HISTOLOGICAL CRITERIA; BLAST-TRANSFORMATION Multiple languages Hematology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28000