Universität zu Köln

ten Freyhaus, H. and Baldus, S. (2016). Paradoxical low-flow low-gradient aortic stenosis. Internist, 57 (4). S. 317 - 323. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1289

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Abstract

In approximately one third of patients presenting with suspected severe aortic stenosis, there is a discrepancy between a severely reduced aortic valve opening area (< 1 cm(2)) and a non-severe increase of the mean transvalvular gradient (< 40 mmHg). In a substantial number of these cases there is evidence of a severe paradoxical low-flow low-gradient aortic stenosis, characterized by a reduced stroke volume index in the setting of a normal left ventricular ejection fraction. This finding should trigger an extensive diagnostic work-up, including echocardiography, stress echocardiography and computed tomography to rule out measurement errors and to identify the cause(s) of the hemodynamic discrepancy. If the diagnosis of a severe paradoxical low-flow low-gradient aortic stenosis is confirmed and, furthermore, the patient is normotensive and reports stenosis-associated symptoms, the feasibility of an aortic valve replacement should be considered.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code ten Freyhaus, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Baldus, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-280100
DOI:	10.1007/s00108-016-0027-9
Journal or Publication Title:	Internist
Volume:	57
Number:	4
Page Range:	S. 317 - 323
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-1289
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PRESERVED EJECTION FRACTION; SEVERITY; DOPPLER; HYPERTENSION; PREDICTORS; MANAGEMENT; AFTERLOAD; INSIGHTS; OUTCOMES Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28010