Universität zu Köln

Hickethier, Tilman ORCID: 0000-0001-9303-9470, Kroeger, Jan Robert, Von Spiczak, Jochen, Baessler, Bettina ORCID: 0000-0002-3244-3864, Pfister, Roman, Maintz, David, Bunck, Alexander C. and Michels, Guido (2016). Non-invasive imaging of bioresorbable coronary scaffolds using CT and MRI: First in vitro experience. Int. J. Cardiol., 206. S. 101 - 107. CLARE: ELSEVIER IRELAND LTD. ISSN 1874-1754

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Abstract

Background: Accurate assessment of coronary stents after PCI using non-invasive imaging remains challenging despite technological improvements. New bioresorbable vascular scaffolds (BVS) have recently become available promising improved non-invasive imaging properties, which however have not be examined specifically yet. Therefore we investigated CT and MRI visualization properties of the only two CE-marked coronary BVSs. Methods: The Abbott Absorb and the Elixir DESolve BVS were placed in plastic tubes filled with contrast agent and scanned with a latest generation CT respectively MR system. For CT image quality was assessed by two blinded, independent readers and in-scaffold diameter difference as well as in-scaffold attenuation difference were measured. For MRI in-scaffold signal intensity, in-scaffold lumen visibility and in-scaffold signal homogeneity were measured. Results: In CTA both BVSs showed no significant difference to nominal tube diameter (DESolve 101%, Absorb 100%) and to nominal tube attenuation (DESolve 96%, Absorb 98%) and were both rated with the highest score for unrestricted lumen visualization. In MRA both BVSs showed unimpaired signal intensity (DESolve 103%, Absorb 100%), lumen visibility (DESolve 92%, Absorb 89%) and lumen homogeneity (DESolve SD 7.1%, Absorb SD 9.5%) when compared to the unstented tube. There was no significant difference between CTA and MRA results of both BVSs. Conclusions: Coronary BVSs show no relevant impairment for subjective and objective measures of in-stent lumen visualization by CT and MRI and will therefore allow reliable non-invasive assessment of coronary artery patency after PCI with deployment of a BVS, which is an (additional) advantage when compared to conventional stents. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hickethier, Tilman UNSPECIFIED orcid.org/0000-0001-9303-9470 UNSPECIFIED Kroeger, Jan Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED Von Spiczak, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED Baessler, Bettina UNSPECIFIED orcid.org/0000-0002-3244-3864 UNSPECIFIED Pfister, Roman UNSPECIFIED UNSPECIFIED UNSPECIFIED Maintz, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Bunck, Alexander C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Michels, Guido UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-283757
DOI:	10.1016/j.ijcard.2016.01.028
Journal or Publication Title:	Int. J. Cardiol.
Volume:	206
Page Range:	S. 101 - 107
Date:	2016
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	1874-1754
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MULTISLICE COMPUTED-TOMOGRAPHY; MAGNETIC-RESONANCE ANGIOGRAPHY; ILIAC ARTERIES; XIENCE PHANTOM; STENTS; LUMEN; PATENCY; IMPLANTATION; ARTIFACTS; MM Multiple languages Cardiac & Cardiovascular Systems Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28375