Gasser, A. -I., Calabrese, P., Kalbe, E., Kessler, J. and Rossier, P. (2016). Cognitive screening in Parkinson's disease: Comparison of the Parkinson Neuropsychometric Dementia Assessment (PANDA) with 3 other short scales. Rev. Neurol., 172 (2). S. 138 - 146. MOULINEAUX CEDEX 9: MASSON EDITEUR. ISSN 2213-0004

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Abstract

Background. - Cognitive screening is crucial in Parkinson's disease (PD). However, there is still a lack of short tools in French. In this study, we aimed to compare the Parkinson Neuropsychometric Dementia Assessment (PANDA) with the Mini Mental Parkinson (MMP), the Mini Mental State Examination (MMSE) and the Clock Test in French-speaking patients. We also aimed to propose cut-off scores for cognitive impairment and dementia for the French language version of the PANDA. Method. - Fifty-one patients with PD took the PANDA, the MMSE, the MMP, and the Clock Test. They also underwent extensive neuropsychological testing by a neuropsychologist who was blinded to the above-mentioned screening test results. Patients were classified as either having normal cognition (n = 15), mild cognitive impairment (n = 20) or dementia (n = 16). Results. - When compared with the three other screening tools, the PANDA exhibited the highest area under the curve (AUC) for both cognitive disorders and dementia. Using the cutoff scores proposed for the German version, the PANDA had 94% specificity and 100% sensitivity for dementia and 100% and 72%, respectively for cognitive disorders. Conclusions. - In our study, the PANDA exhibited a higher discriminative power than the three other tests in detecting cognitive disorders and dementia. In PD patients, the PANDA should thus be considered for the detection of cognitive impairment in routine clinical practice. (C) 2015 Elsevier Masson SAS. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Gasser, A. -I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Calabrese, P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kalbe, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kessler, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rossier, P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-285203
DOI: 10.1016/j.neurol.2015.08.004
Journal or Publication Title: Rev. Neurol.
Volume: 172
Number: 2
Page Range: S. 138 - 146
Date: 2016
Publisher: MASSON EDITEUR
Place of Publication: MOULINEAUX CEDEX 9
ISSN: 2213-0004
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SOCIETY TASK-FORCE; DIAGNOSTIC-CRITERIA; ALZHEIMERS-DISEASE; IMPAIRMENT; RECOMMENDATIONS; SENSITIVITY; BEDSIDE; TOOLMultiple languages
Clinical NeurologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/28520

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