Universität zu Köln

Kruis, Wolfgang and Nguyen, G. Phuong (2016). Iron Deficiency, Zinc, Magnesium, Vitamin Deficiencies in Crohn's Disease: Substitute or Not? Dig. Dis., 34 (1-2). S. 105 - 112. BASEL: KARGER. ISSN 1421-9875

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Abstract

Inflammatory bowel disease (IBD) is characterized by inflammatory reactions, complications, extraintestinal manifestations and a loss of intestinal functions, for example, failures of absorption and secretion. According to intestinal dysfunction, a wide array of pathogenetic pathways is existing leading to iron deficiency and numerous vitamins as well as trace element deficiencies. Complications, symptoms and signs of those deficiencies are common in IBD with varying degrees of clinical significance. This review focuses on selected micronutrients including iron, zinc, magnesium and some vitamins. Epidemiology with respect to IBD, pathophysiology, diagnosis and clinical aspects are addressed. Finally, some suggestions for treatment of deficient situations are discussed. In conclusion, some micronutrients have significant impact on complications and quality of life in IBD. Deficiencies may even influence the course of the disease. Those deficiencies should be thoroughly supplemented. (C) 2016 S. Karger AG, Basel

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kruis, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED Nguyen, G. Phuong UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-290445
DOI:	10.1159/000443012
Journal or Publication Title:	Dig. Dis.
Volume:	34
Number:	1-2
Page Range:	S. 105 - 112
Date:	2016
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1421-9875
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INFLAMMATORY-BOWEL-DISEASE; RISK-FACTORS; ANEMIA; PREVALENCE; MANAGEMENT; DIAGNOSIS; PATIENT Multiple languages Gastroenterology & Hepatology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/29044