Scaal, Martin (2016). Early development of the vertebral column. Semin. Cell Dev. Biol., 49. S. 83 - 92. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. ISSN 1084-9521

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Abstract

The segmental organization of the vertebrate body is most obviously visible in the vertebral column, which consists of a series of vertebral bones and interconnecting joints and ligaments. During embryo genesis, the vertebral column derives from the somites, which are the primary segments of the embryonic paraxial mesoderm. Anatomical, cellular and molecular aspects of vertebral column development have been of interest to developmental biologists for more than 150 years. This review briefly summarizes the present knowledge on early steps of vertebral column development in amniotes, starting from sclerotome formation and leading to the establishment of the anatomical bauplan of the spine composed of vertebral bodies, vertebral arches, intervertebral discs and ribs, and their specific axial identities along the body axis. (C) 2015 Elsevier Ltd. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Scaal, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-291262
DOI: 10.1016/j.semcdb.2015.11.003
Journal or Publication Title: Semin. Cell Dev. Biol.
Volume: 49
Page Range: S. 83 - 92
Date: 2016
Publisher: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Place of Publication: LONDON
ISSN: 1084-9521
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
AXIAL SKELETON DEVELOPMENT; BONE MORPHOGENETIC PROTEINS; AVIAN EMBRYOS; HOX GENES; HOMEOBOX GENE; INTERVERTEBRAL DISCS; PARAXIAL MESODERM; CHICK-EMBRYOS; NEURAL CREST; MOUSE EMBRYOMultiple languages
Cell Biology; Developmental BiologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/29126

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