Zimmer, Philipp, Baumann, Freerk T., Oberste, Max, Wright, Peter, Garthe, Alexander, Schenk, Alexander, Elter, Thomas, Galvao, Daniel A., Bloch, Wilhelm, Hubner, Sven T. and Wolf, Florian (2016). Effects of Exercise Interventions and Physical Activity Behavior on Cancer Related Cognitive Impairments: A Systematic Review. Biomed Res. Int., 2016. LONDON: HINDAWI LTD. ISSN 2314-6141

Full text not available from this repository.

Abstract

This systematic review analyzes current data on effects of exercise interventions and physical activity behavior on objective and subjective cancer related cognitive impairments (CRCI). Out of the 19 studies which met all inclusion criteria, five RCTs investigated rodents, whereas the other 14 trials explored humans and these included six RCTs, one controlled trial, two prospective noncontrolled trials, one case series, one observational study, and three cross-sectional studies. The results from animal models revealed positive effects of exercise during and after chemotherapy or radiation on structural alterations of the central nervous system, physiological as well as neuropsychological outcomes. The overall study quality in patient studies was poor. The current data on intervention studies showed preliminary positive effects of Asian-influenced movement programs (e.g., Yoga) with benefits on self-perceived cognitive functions as well as a reduction of chronic inflammation for breast cancer patients in the aftercare. Exercise potentially contributes to the prevention and rehabilitation of CRCI. Additional RCTs with standardized neuropsychological assessments and controlling for potential confounders are needed to confirm and expand preliminary findings.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Zimmer, PhilippUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baumann, Freerk T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Oberste, MaxUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wright, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Garthe, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schenk, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Elter, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Galvao, Daniel A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bloch, WilhelmUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hubner, Sven T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wolf, FlorianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-292421
DOI: 10.1155/2016/1820954
Journal or Publication Title: Biomed Res. Int.
Volume: 2016
Date: 2016
Publisher: HINDAWI LTD
Place of Publication: LONDON
ISSN: 2314-6141
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ADULT HIPPOCAMPAL NEUROGENESIS; QUALITY-OF-LIFE; EARLY BREAST-CANCER; OLDER-ADULTS; CHEMOTHERAPY; WOMEN; METAANALYSIS; ASSOCIATION; FITNESS; MEMORYMultiple languages
Biotechnology & Applied Microbiology; Medicine, Research & ExperimentalMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/29242

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item