Rokohl, Alexander C., Loreck, Niklas, Matos, Philomena A. Wawer, Zwingelberg, Sarah, Augustin, Max, Dewald, Felix, Grajewski, Rafael S., Klein, Florian, Lehmann, Clara and Heindl, Ludwig M. (2020). More than loss of taste and smell: burning watering eyes in coronavirus disease 2019. Clin. Microbiol. Infect., 26 (11). OXFORD: ELSEVIER SCI LTD. ISSN 1469-0691
Full text not available from this repository.Abstract
Objectives: To evaluate ocular symptoms in European non-hospitalized patients with severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) and to investigate associations with the demographic data as well as nasal and general physical symptoms. Methods: In this prospective, observational study, 108 non-hospitalized patients with PCR-confirmed SARS-CoV-2 infection not requiring intensive care were asked about disease-associated ocular symptoms, demographic data, as well as general physical and nasal symptoms using a standardized questionnaire. Total ocular symptom score (TOSS) was evaluated during and, retrospectively, before development of coronavirus disease 2019 (COVID-19). Associations between TOSS and demographic data as well as general and nasal symptoms were evaluated. Results: Seventy-five of the 108 COVID-19 patients (69.4%) had at least one ocular symptom during COVID-19. The most common symptoms included burning sensations in 39 (36.1%), epiphora in 37 (34.3%) and redness in 28 (25.9%), compatible with conjunctivitis. These symptoms occurred 1.96 +/- 3.17 days after the beginning of COVID-19 and were mild. TOSS was significantly higher during COVID-19 (1.27 +/- 1.85) than before the infection (0.33 +/- 1.04; p < 0.001). There were no significant associations between TOSS and gender (b coefficient-0.108; p 0.302), age (-0.024; p 0.816), rhinorrhoea (-0.127; p 0.353), nasal itching (-0.026; p 0.803), sneezing (0.099; p 0.470), nasal congestion (-0.012; p 0.930), cough (-0.079; p 0.450), headache (0.102; p 0.325), sore throat (0.208; p 0.052), or fever (0.094; p 0.361). Conclusions: Ocular involvement in European non-hospitalized individuals with COVID-19 seems to be highly underestimated. Overall, these ocular symptoms, including burning sensations, epiphora and redness, seem to be mild and to not need treatment. (c) 2020 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
| Item Type: | Journal Article | ||||||||||||||||||||||||||||||||||||||||||||
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| URN: | urn:nbn:de:hbz:38-312778 | ||||||||||||||||||||||||||||||||||||||||||||
| DOI: | 10.1016/j.cmi.2020.08.018 | ||||||||||||||||||||||||||||||||||||||||||||
| Journal or Publication Title: | Clin. Microbiol. Infect. | ||||||||||||||||||||||||||||||||||||||||||||
| Volume: | 26 | ||||||||||||||||||||||||||||||||||||||||||||
| Number: | 11 | ||||||||||||||||||||||||||||||||||||||||||||
| Date: | 2020 | ||||||||||||||||||||||||||||||||||||||||||||
| Publisher: | ELSEVIER SCI LTD | ||||||||||||||||||||||||||||||||||||||||||||
| Place of Publication: | OXFORD | ||||||||||||||||||||||||||||||||||||||||||||
| ISSN: | 1469-0691 | ||||||||||||||||||||||||||||||||||||||||||||
| Language: | English | ||||||||||||||||||||||||||||||||||||||||||||
| Faculty: | Unspecified | ||||||||||||||||||||||||||||||||||||||||||||
| Divisions: | Unspecified | ||||||||||||||||||||||||||||||||||||||||||||
| Subjects: | no entry | ||||||||||||||||||||||||||||||||||||||||||||
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| URI: | http://kups.ub.uni-koeln.de/id/eprint/31277 |
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