Universität zu Köln

Styczen, Hanna ORCID: 0000-0002-9623-4156, Fischer, Sebastian, Yeo, Leonard L. L., Yong-Qiang Tan, Benjamin, Maurer, Christoph J., Berlis, Ansgar, Abdullayev, Nuran, Kabbasch, Christoph, Kastrup, Andreas, Papanagiotou, Panagiotis, Clajus, Christin, Lobsien, Donald, Piechowiak, Eike, Kaesmacher, Johannes and Maus, Volker . Approaching the Boundaries of Endovascular Treatment in Acute Ischemic Stroke Multicenter Experience with Mechanical Thrombectomy in Vertebrobasilar Artery Branch Occlusions. Clin. Neuroradiol.. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1869-1447

Full text not available from this repository.

Abstract

Purpose Little is known about catheter-based endovascular treatment of vertebrobasilar artery branch occlusion (VEBABO) in acute ischemic stroke (AIS). Nonetheless, the experience of mechanical thrombectomy (MT) in distal small sized arteries of the anterior circulation seems promising in AIS. In this multicenter study, we report the feasibility, efficacy and safety of MT in VEBABO. Methods Retrospective analysis of consecutive AIS patients treated with MT due to VEBABO including posterior and anterior inferior cerebellar artery (PICA, AICA) and superior cerebellar artery (SCA) occlusions at seven tertiary care centers between January 2013 and May 2020. Baseline demographics and angiographic outcomes including recanalization success of the affected cerebellar arteries and procedural complications were recorded. Clinical outcomes were evaluated by the modified Rankin scale (mRS) at discharge and 90 days. Results Out of 668 endovascularly treated posterior circulation strokes we identified 16 (0.02%) cases with MT for VEBABO. Most frequently, MT of the SCA was done (13/16, 81%). Most VEBABOs occurred after MT of initial basilar/posterior cerebral artery occlusion (9/16, 56%). In 10/16 (63%) procedures, the affected VEBABO was successfully recanalized. Out of four patients three (75%) with isolated VEBABO had benefited from endovascular therapy. Subarachnoid hemorrhage was observed in 3/16 (19%) procedures. The rate of favorable outcome (mRS <= 2) was 40% at discharge and 47% at 90-day follow-up. Mortality was 13% (2/15). Conclusion The use of MT for VEBABO is rare but appears to be feasible and effective; however, the comparatively high rate of procedure-related hemorrhage highlights that the indications for MT in these occlusion sites should be carefully weighed up.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Styczen, Hanna UNSPECIFIED orcid.org/0000-0002-9623-4156 UNSPECIFIED Fischer, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Yeo, Leonard L. L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Yong-Qiang Tan, Benjamin UNSPECIFIED UNSPECIFIED UNSPECIFIED Maurer, Christoph J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Berlis, Ansgar UNSPECIFIED UNSPECIFIED UNSPECIFIED Abdullayev, Nuran UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Kastrup, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Papanagiotou, Panagiotis UNSPECIFIED UNSPECIFIED UNSPECIFIED Clajus, Christin UNSPECIFIED UNSPECIFIED UNSPECIFIED Lobsien, Donald UNSPECIFIED UNSPECIFIED UNSPECIFIED Piechowiak, Eike UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaesmacher, Johannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Maus, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-314283
DOI:	10.1007/s00062-020-00970-7
Journal or Publication Title:	Clin. Neuroradiol.
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1869-1447
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RECANALIZATION; GUIDELINES; MANAGEMENT Multiple languages Clinical Neurology; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31428