Celik, Erkan, Pennig, Lenhard, Laukamp, Kai Roman, Hammes, Jochen, Maintz, David, Kabbasch, Christoph, Abdullayev, Nuran ORCID: 0000-0003-4522-537X, Bunck, Alexander Christian, Achenbach, Tobias, Caldeira, Liliana and Hickethier, Tilman (2020). Are left atrial diverticula and left-sided septal pouches relevant additional findings in cardiac CT? Correlation between left atrial outpouching structures and ischemic brain alterations. Int. J. Cardiol., 317. S. 216 - 221. CLARE: ELSEVIER IRELAND LTD. ISSN 1874-1754

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Abstract

Purpose: To evaluate the correlation between left atrial diverticula (LAD) and left-sided septal pouches (LSSP) with ischemic brain alterations in MRI Methods: A retrospective analysis of 174 patients who received both, a dedicated cardiac CT angiography (CCTA) and a brain MRI examination was performed. Two radiologists independently reviewed all examinations for the presence of LAD and LSSP as well as ischemic alterations of the brain. Subsequently, the correlation between these cardiac and cerebral findings as well as to other potentially related risk factors was assessed. Results: 71 LAD (total prevalence 41%) and 65 LSSP (total prevalence 37%) were identified in 174 patients. Combined prevalence was 10%. Ischemic brain alterations were found in patients with a LAD in 42.3% (30/71) and with a LSSP in 64.6% (42/65). Patients without any anatomical variant in the left atrium showed ischemic brain alterations in 39.4% (26/66). The presence of a LSSP was associated with an increased risk for ischemic brain alterations in multivariate logistic regression analysis after adjusting for other risk factors (OR = 3.57, 95% CI = 0.51-2.09, p < .01). Conclusion: In our study cohort LAD and LSSP are highly prevalent anatomical structures within the left atrium. Patients with LSSP showed an approximated 3.5-fold higher probability for ischemic brain alterations. Therefore, LSSP should be considered as a potential risk factor for cardioembolic strokes and its presence should be stated in cardiac CT reports. (c) 2020 Elsevier B.V. All rights reserved.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Celik, ErkanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pennig, LenhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laukamp, Kai RomanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hammes, JochenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maintz, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kabbasch, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Abdullayev, NuranUNSPECIFIEDorcid.org/0000-0003-4522-537XUNSPECIFIED
Bunck, Alexander ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Achenbach, TobiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Caldeira, LilianaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hickethier, TilmanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-314894
DOI: 10.1016/j.ijcard.2020.05.038
Journal or Publication Title: Int. J. Cardiol.
Volume: 317
Page Range: S. 216 - 221
Date: 2020
Publisher: ELSEVIER IRELAND LTD
Place of Publication: CLARE
ISSN: 1874-1754
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ACCESSORY APPENDAGES; CRYPTOGENIC STROKE; RISK-FACTOR; FIBRILLATION; ABLATION; STENOSIS; MRIMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/31489

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