Universität zu Köln

Gabor, Erika, Cinege, Gyongyi, Csordas, Gabor, Rusvai, Miklos, Honti, Viktor, Kolics, Balazs, Torok, Tibor, Williams, Michael J., Kurucz, Eva and Ando, Istvan (2020). Identification of reference markers for characterizing honey bee (Apis mellifera) hemocyte classes. Dev. Comp. Immunol., 109. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0089

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Abstract

Cell mediated immunity of the honey bee (Apis mellifera) involves the activity of several hemocyte populations, currently defined by morphological features and lectin binding characteristics. The objective of the present study was to identify molecular markers capable of characterizing subsets of honey bee hemocytes. We developed and employed monoclonal antibodies with restricted reactions to functionally distinct hemocyte subpopulations. Melanizing cells, known as oenocytoids, were defined by an antibody to prophenoloxidase, aggregating cells were identified by the expression of Hemolectin, and phagocytic cells were identified by a marker expressed on granulocytes. We anticipate that this combination of antibodies not only allows for the detection of functionally distinct hemocyte subtypes, but will help to further the exploration of hematopoietic compartments, as well as reveal details of the honey bee cellular immune defense against parasites and microbes.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gabor, Erika UNSPECIFIED UNSPECIFIED UNSPECIFIED Cinege, Gyongyi UNSPECIFIED UNSPECIFIED UNSPECIFIED Csordas, Gabor UNSPECIFIED UNSPECIFIED UNSPECIFIED Rusvai, Miklos UNSPECIFIED UNSPECIFIED UNSPECIFIED Honti, Viktor UNSPECIFIED UNSPECIFIED UNSPECIFIED Kolics, Balazs UNSPECIFIED UNSPECIFIED UNSPECIFIED Torok, Tibor UNSPECIFIED UNSPECIFIED UNSPECIFIED Williams, Michael J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kurucz, Eva UNSPECIFIED UNSPECIFIED UNSPECIFIED Ando, Istvan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-325422
DOI:	10.1016/j.dci.2020.103701
Journal or Publication Title:	Dev. Comp. Immunol.
Volume:	109
Date:	2020
Publisher:	ELSEVIER SCI LTD
Place of Publication:	OXFORD
ISSN:	1879-0089
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language IMMUNE-RESPONSES; CELL-TYPE; EXPRESSION; PROPHENOLOXIDASE; ANTIBODY Multiple languages Fisheries; Immunology; Zoology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32542