Universität zu Köln

Duran, Ibrahim ORCID: 0000-0003-4044-8822, Martakis, Kyriakos, Alberg, Evelyn, Jackels, Miriam, Ewert, Kim Ramona and Schoenau, Eckhard (2020). Association of Trunk/Leg Fat Mass Ratio with Low-Density Lipoproteins-Cholesterol and Triglycerides Concentration in Children and Adolescents: A Cross-Sectional, Retrospective Study. Child Obes., 16 (6). S. 428 - 440. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 2153-2176

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Abstract

Background:Increased central (or abdominal) fat mass has been associated with cardiometabolic risk factors such as high low-density lipoproteins (LDL)-cholesterol or triglycerides (TG) concentration in children. Objectives:To generate pediatric reference centiles for trunk/leg fat mass ratio (T2L) (assessed by dual-energy X-ray absorptiometry [DXA]) and to evaluate the association of LDL-cholesterol and TG concentrations with T2L in children and adolescents.Methods:Data of the National Health and Nutrition Examination Survey (1999-2004) were used to determine total and regional fat mass by DXA of the participants (aged 8-19 years) who had also an examination of LDL-cholesterol and TG concentrations. Fat mass was assessed by DXA-determined fat mass index (FMI). Central fat mass was quantified by T2L. Results:The DXA results of 6538 children and adolescents (2629 females) were used to generate reference centiles for T2L. In girls, T2L was significantly associated with high LDL-cholesterol and TG concentration (odds ratio [OR] adjusted to FMI 1.69), (95% confidence interval [CI] 1.20-2.40), and 1.45 (95% CI 1.11-1.91,p = 0.003 andp = 0.008). In boys, T2L was significantly associated only with high TG concentration (OR adjusted to FMI 1.81 [95% CI 1.52-2.19,p < 0.001]). Conclusions:A central fat distribution seemed to be an independent risk factor for high TG concentrations in children and for high LDL-cholesterol only in girls. The first ethnicity-specific, pediatric reference centiles for T2L were presented.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Duran, Ibrahim UNSPECIFIED orcid.org/0000-0003-4044-8822 UNSPECIFIED Martakis, Kyriakos UNSPECIFIED UNSPECIFIED UNSPECIFIED Alberg, Evelyn UNSPECIFIED UNSPECIFIED UNSPECIFIED Jackels, Miriam UNSPECIFIED UNSPECIFIED UNSPECIFIED Ewert, Kim Ramona UNSPECIFIED UNSPECIFIED UNSPECIFIED Schoenau, Eckhard UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-329230
DOI:	10.1089/chi.2019.0307
Journal or Publication Title:	Child Obes.
Volume:	16
Number:	6
Page Range:	S. 428 - 440
Date:	2020
Publisher:	MARY ANN LIEBERT, INC
Place of Publication:	NEW ROCHELLE
ISSN:	2153-2176
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CARDIOMETABOLIC RISK-FACTORS; TO-HEIGHT RATIO; WAIST CIRCUMFERENCE; ABDOMINAL FAT; INSULIN SENSITIVITY; BODY-FAT; RESISTANCE EXERCISE; INDIAN CHILDREN; SEX-DIFFERENCES; METABOLIC RISK Multiple languages Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32923