Universität zu Köln

Jordan, Jens, Ricci, Fabrizio ORCID: 0000-0002-1401-6623, Hoffmann, Fabian ORCID: 0000-0002-3199-9924, Hamrefors, Viktor and Fedorowski, Artur ORCID: 0000-0002-5352-6327 (2020). Orthostatic Hypertension Critical Appraisal of an Overlooked Condition. Hypertension, 75 (5). S. 1151 - 1159. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1524-4563

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Abstract

Orthostatic hypertension, which appears to be mediated through excess neurohumoral activation while standing, is a common blood pressure trait among patients with and without arterial hypertension. However, lack of consensus regarding the definition of orthostatic hypertension makes it difficult to assess the true prevalence of this condition. Orthostatic hypertension appears to predict the risk for progression to arterial hypertension in younger and risk of cardiovascular morbidity and mortality in older persons. Yet, the risk may differ between populations. Whether orthostatic hypertension indicates a generally increased risk of death, constitutes an intermediate variable in the causal pathway of cardiovascular risk factors, a simple measure of disease severity, or an independently acting mechanism is not known. Since both orthostatic hypotension and orthostatic hypertension herald increased risk of cardiovascular disease, it appears reasonable to screen the patients for abnormal orthostatic blood pressure responses using simple orthostatic testing. However, how presence of orthostatic hypertension may affect clinical management decisions such as the choice of antihypertensive drugs is currently difficult to ascertain. Clearly, this issue deserves more attention.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Jordan, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Ricci, Fabrizio UNSPECIFIED orcid.org/0000-0002-1401-6623 UNSPECIFIED Hoffmann, Fabian UNSPECIFIED orcid.org/0000-0002-3199-9924 UNSPECIFIED Hamrefors, Viktor UNSPECIFIED UNSPECIFIED UNSPECIFIED Fedorowski, Artur UNSPECIFIED orcid.org/0000-0002-5352-6327 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-335833
DOI:	10.1161/HYPERTENSIONAHA.120.14340
Journal or Publication Title:	Hypertension
Volume:	75
Number:	5
Page Range:	S. 1151 - 1159
Date:	2020
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1524-4563
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BLOOD-PRESSURE RESPONSE; TARGET-ORGAN DAMAGE; ALL-CAUSE MORTALITY; CARDIOVASCULAR RISK; MONOGENIC HYPERTENSION; TASK-FORCE; HYPOTENSION; MANAGEMENT; INDIVIDUALS; ASSOCIATION Multiple languages Peripheral Vascular Disease Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/33583