Vaganian, Lusine ORCID: 0000-0001-9718-4106, Bussmann, Sonja, Gerlach, Alexander L. ORCID: 0000-0001-6794-5349, Kusch, Michael, Labouvie, Hildegard and Cwik, Jan C. (2020). Critical consideration of assessment methods for clinically significant changes of mental distress after psycho-oncological interventions. Int. J. Methods Psychiatr. Res., 29 (2). HOBOKEN: WILEY. ISSN 1557-0657

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Abstract

Objectives Considering the heterogeneity of cancer entities and the associated disease progression, personalized care of patients is increasingly emphasized in psycho-oncology. This individualization makes the use of measurements of individual clinically significant change important when studying the efficacy and effectiveness of psycho-oncological care. Two conceptualizations for the measurement of clinical significance are critically contrasted in this study: the Reliable Change Index (RCI) and the Minimal Important Difference (MID) method. Methods In total, 2,121 cancer patients participated in the study and a subsample of 708 patients was reassessed about 4 months later. Psychological distress was measured using the Hospital Anxiety and Depression Scale. We evaluated two measures of clinical significance (RCI, MID) by comparing the respective numbers of improved, unimproved, and deteriorated patients. Results Individually significant changes were observed with both methods; however, determined rates of improvement differed substantially: MID (66.67%) and RCI (48.23%). Most importantly, according to MID, 17.93% of patients were identified as being improved, although their respective improvements were not statistically significant and thus unreliable. Conclusions The benefits of RCI outweigh MID, and therefore, the RCI is recommended as a measure to assess change.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Vaganian, LusineUNSPECIFIEDorcid.org/0000-0001-9718-4106UNSPECIFIED
Bussmann, SonjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gerlach, Alexander L.UNSPECIFIEDorcid.org/0000-0001-6794-5349UNSPECIFIED
Kusch, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Labouvie, HildegardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cwik, Jan C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-344181
DOI: 10.1002/mpr.1821
Journal or Publication Title: Int. J. Methods Psychiatr. Res.
Volume: 29
Number: 2
Date: 2020
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1557-0657
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
STATISTICAL SIGNIFICANCE; IMPORTANT DIFFERENCE; MEANINGFUL CHANGE; DEPRESSION SCALE; HOSPITAL ANXIETY; HEALTH-STATUS; CANCER; PSYCHOTHERAPY; DIAGNOSIS; VALIDITYMultiple languages
PsychiatryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/34418

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