Universität zu Köln

Beckmann, Agnes, Nicolini, Luis Fernando, Grevenstein, David, Backes, Hermann, Oikonomidis, Stavros, Sobottke, Rolf, Kobbe, Philipp, Hildebrand, Frank and Stoffel, Marcus (2020). Biomechanical In Vitro Test of a Novel Dynamic Spinal Stabilization System Incorporating Polycarbonate Urethane Material Under Physiological Conditions. J. Biomech. Eng.-Trans. ASME, 142 (1). NEW YORK: ASME. ISSN 1528-8951

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Abstract

Posterior dynamic stabilization systems (PDSS) were developed to provide stabilization to pathologic or hypermobile spinal segments while maintaining the healthy biomechanics of the spine. Numerous novel dynamic devices incorporate the temperature and moisture dependent material polycarbonate urethane (PCU) due to its mechanical properties and biocompatibility. In this study, standardized pure moment in vitro tests were carried out on human lumbar spines to evaluate the performance of a device containing PCU. An environmental chamber with controlled moisture and temperature was included in the setup to meet the requirements of testing under physiological conditions. Three test conditions were compared: (1) native spine, (2) dynamic instrumentation, and (3) dynamic instrumentation with decompression. The ranges of motion, centers of rotation, and relative pedicle screw motions were evaluated. The device displayed significant stiffening in flexion-extension, lateral bending, and axial rotation load directions. A reduction of the native range of motion diminished the stiffening effect along the spinal column and has the potential to reduce the risk of the onset of degeneration of an adjacent segment. In combination with decompression, the implant decreased the native range of motion for flexion-extension and skew bending, but not for lateral bending and axial rotation. Curve fittings using the sigmoid function were performed to parameterize all load-deflection curves in order to enhance accurate numerical model calibrations and comparisons. The device caused a shift of the center of rotation (COR) in the posterior and caudal direction during flexion-extension loading.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Beckmann, Agnes UNSPECIFIED UNSPECIFIED UNSPECIFIED Nicolini, Luis Fernando UNSPECIFIED UNSPECIFIED UNSPECIFIED Grevenstein, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Backes, Hermann UNSPECIFIED UNSPECIFIED UNSPECIFIED Oikonomidis, Stavros UNSPECIFIED UNSPECIFIED UNSPECIFIED Sobottke, Rolf UNSPECIFIED UNSPECIFIED UNSPECIFIED Kobbe, Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Hildebrand, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Stoffel, Marcus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-351088
DOI:	10.1115/1.4044242
Journal or Publication Title:	J. Biomech. Eng.-Trans. ASME
Volume:	142
Number:	1
Date:	2020
Publisher:	ASME
Place of Publication:	NEW YORK
ISSN:	1528-8951
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DISC DEGENERATION; PEDICLE SCREWS; LOAD-BEARING; SURGERY; DECOMPRESSION; STENOSIS Multiple languages Biophysics; Engineering, Biomedical Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/35108