Universität zu Köln

Houbois, Christian, Haneder, Stefan, Merkt, Martin, Morelli, John, Weiss, Kilian, Hellmich, Martin, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Maintz, David and Puesken, Michael (2020). Semiautomated Renal Cortex Volumetry in Spectral Computed Tomography: Effect of Monoenergetic Reconstructions on Measurement Precision and Interobserver Variability. J. Comput. Assist. Tomogr., 44 (1). S. 138 - 145. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1532-3145

Full text not available from this repository.

Abstract

Objective The aim of this study was to determine the influence of virtual monoenergetic images (vMEIs) on renal cortex volumetry (RCV) and estimation of split-renal function. Methods Twenty-five patients (mean +/- SD, 64.7 +/- 9.9 years) underwent a contrast-enhanced dual-layer spectral detector computed tomography. Images were reconstructed with a reference standard (iterative model reconstruction, IMRRef), a newly spectral detector computed tomography algorithm (SPcon) and vMEI at 40, 60, 80, 100, and 120 keV. Two blinded independent readers performed RCV on all data sets with a semiautomated tool. Results Total kidney volume was up to 15% higher in vMEI at 40/60 keV compared with IMRRef (P < 0.001). Total kidney volume with vMEI at 80/100 keV was similar to IMRRef (P < 0.001). Split-renal function was similar in all reconstructions at approximately 50% +/- 3%. Bland-Altman analysis showed no significant differences (P > 0.05), except for 40 keV versus SPcon (P < 0.05). The time required to perform RCV was reasonable, approximately 4 minutes, and showed no significant differences among reconstructions. Interreader agreement was greatest with vMEI at 80 keV (r = 0.68; 95% confidence interval, 0.39-0.85; P < 0.0002) followed by IMRRef images (r = 0.67; 95% confidence interval, 0.37-0.84; P < 0.0003). IMRRef showed the highest mean Hounsfield unit for cortex/medulla of 223.4 +/- 73.7/62.5 +/- 19.7 and a ratio of 3.7. Conclusions Semiautomated RCV performed with vMEI and IMRRef/SPcon is feasible and showed no clinically relevant differences with regard to split-renal function. Low-kiloelectron volt vMEI showed greater tissue contrast and total kidney volume but no benefit for RCV. Moderate-kiloelectron volt vMEI (80 keV) results were similar to IMRRef with a faster postprocessing time.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Houbois, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Haneder, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Merkt, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Morelli, John UNSPECIFIED UNSPECIFIED UNSPECIFIED Weiss, Kilian UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Chon, Seung-Hun UNSPECIFIED orcid.org/0000-0002-8923-6428 UNSPECIFIED Maintz, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Puesken, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-351863
DOI:	10.1097/RCT.0000000000000952
Journal or Publication Title:	J. Comput. Assist. Tomogr.
Volume:	44
Number:	1
Page Range:	S. 138 - 145
Date:	2020
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1532-3145
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language STATISTICAL ITERATIVE RECONSTRUCTION; FILTERED BACK-PROJECTION; DETECTOR CT; IMAGE QUALITY; PARAMETERS Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/35186