Universität zu Köln

Horn, L. -C., Beckmann, M. W., Follmann, M., Koch, M. C., Mallmann, P., Marnitz, S. and Schmidt, D. (2015). S3 guidelines on diagnostics and treatment of cervical cancer. Demands on pathology. Pathologe, 36 (6). S. 585 - 594. NEW YORK: SPRINGER. ISSN 1432-1963

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Abstract

Between 2011 and the end of 2014 the former consensus S2k guidelines for the diagnostics and treatment of cervical cancer were updated and upgraded to S3 level, methodologically based on the regulations of the German Cancer Society (DKG). The present article summarizes the relevant aspects for the sectioning, histopathological workup, diagnostics and reporting for the pathology of invasive cancer of the uterine cervix. The recommendations are based on the most recent World Health Organization (WHO) and TNM classification systems and consider the needs of the clinician for appropriate surgical and radiotherapeutic treatment of patients. Detailed processing rules of colposcopy-guided diagnostic biopsies, conization and trachelectomy as well as for radical hysterectomy specimens and lymph node resection (including sentinel lymph node resection) are given. In the guidelines deep stromal invasion in macroinvasive cervical cancer is defined for the first time as tumor infiltration of > 66 % of the cervical stromal wall. Furthermore, morphological prognostic factors for microinvasive and macroinvasive cervical cancer are summarized.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Horn, L. -C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Beckmann, M. W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Follmann, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Koch, M. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Marnitz, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-388059
DOI:	10.1007/s00292-015-0114-z
Journal or Publication Title:	Pathologe
Volume:	36
Number:	6
Page Range:	S. 585 - 594
Date:	2015
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1963
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SQUAMOUS-CELL CARCINOMA; GYNECOLOGIC-ONCOLOGY-GROUP; LYMPHOVASCULAR SPACE INVASION; LYMPH-NODE MICROMETASTASIS; UTERINE CERVIX; PROGNOSTIC-FACTORS; RADICAL HYSTERECTOMY; MULTIVARIATE-ANALYSIS; PERINEURAL INVASION; METASTATIC-DISEASE Multiple languages Pathology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/38805